ANGPT2

Gene Name		angiopoietin 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Projection
	Molecular Function	Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding
	Biological Process	Angiogenesis Response To Hypoxia Signal Transduction Germ Cell Development Blood Coagulation Response To Radiation Response To Mechanical Stimulus Response To Glucose Negative Regulation Of Cell-substrate Adhesion Response To Organic Cyclic Compound Response To Activity Negative Regulation Of Angiogenesis Organ Regeneration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Tie Signaling Pathway Leukocyte Migration Negative Regulation Of Positive Chemotaxis Maternal Process Involved In Female Pregnancy Cellular Response To Growth Factor Stimulus Glomerulus Vasculature Development
Pathways		Tie2 Signaling Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: ANGPT1 ANXA7 CDKN1A CSNK2B TEK
Entrez ID		285
HPRD ID		03563
Ensembl ID		ENSG00000091879
Uniprot IDs		O15123
PDB IDs		1Z3S 1Z3U 2GY7 4JZC
Enriched GO Terms of Interacting Partners?		Tie Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Cytokine Secretion Involved In Immune Response Regulation Of Epithelial Cell Migration Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Phosphorylation Regulation Of Protein Localization To Nucleus Regulation Of Kinase Activity Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Phosphorylation Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Protein Modification Process Regulation Of Intracellular Protein Transport Regulation Of Vascular Permeability Regulation Of Protein Phosphorylation Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Phosphorylation Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Hemostasis Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Organ Regeneration Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Transferase Activity Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Body Fluid Levels Regulation Of Cell Migration Regulation Of Protein Transport Regulation Of Cell Motility Regulation Of Peptidyl-serine Phosphorylation Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Cellular Protein Metabolic Process Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade
Tagcloud ?		clonality clones comings depicting deregulated engrafted gammaretroviral genotoxicity gv harboring hematopoiesis hsc hscs il2rg immunodeficient insertion insertional integrating integrations leukemogenesis ltr nsg overrepresentation resembling transplanted underscore utilizing vicinity