TMEM248 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM248	ARL6IP1
Description		transmembrane protein 248	ARL6 interacting reticulophagy regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways
Drugs
Diseases
GWAS			Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ANKRD46 ARL6IP1 ARLN BARD1 BRICD5 CLDN19 FAM3C GPR25 GPR37L1 GRM2 LEPROTL1 LHFPL5 MAL MALL RUSF1 RXFP3 SLC35B2 SLC41A1 SYNE4 SYS1 TMEM147 TMEM239 TMEM86B TRARG1 VSTM1 YIF1A YIPF1	78 interacting genes: ACSF2 AQP6 ARL4D ARL6 BCL2L13 C19orf18 CERT1 DIABLO DRC4 EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35H1 SLC61A1 SLC71A2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		55069	23204
HPRD ID		08541	09641
Ensembl ID		ENSG00000106609	ENSG00000170540
Uniprot IDs		Q9NWD8	Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Establishment Of Protein Localization To Membrane Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath	Lipid Binding Phosphatidylinositol Binding Cellular Localization Establishment Of Protein Localization Retromer Complex Intracellular Transport Protein Transport Membrane Establishment Of Localization In Cell Leptin Receptor Binding Localization Within Membrane Intracellular Protein Transport Early Endosome To Golgi Transport Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Endosome Phosphatidylinositol-4-phosphate Binding Transferrin Receptor Binding Negative Regulation Of Early Endosome To Late Endosome Transport Endosomal Transport Endocytic Recycling Cytosolic Transport Early Endosome Membrane Phosphatidylinositol-3-phosphate Binding Protein Targeting To Golgi Apparatus Protein Binding Mitochondrial Matrix Early Endosome Retromer, Tubulation Complex Golgi Vesicle Budding Cargo Adaptor Activity Establishment Of Protein Localization To Plasma Membrane Insulin Receptor Binding Vesicle-mediated Transport Organelle Organization Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport Succinate Metabolic Process Lamellipodium Morphogenesis Epidermal Growth Factor Receptor Binding Vesicle Budding From Membrane Protein Localization To Membrane Vesicle Organization Positive Regulation Of Exocytosis Regulation Of Establishment Of Protein Localization Membrane Organization Golgi Cisterna Regulation Of Protein Localization
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