TPRX1 and FANCG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPRX1	FANCG
Description		tetrapeptide repeat homeobox 1	FA complementation group G
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Speck Fanconi Anaemia Nuclear Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Damaged DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Maternal-to-zygotic Transition Of Gene Expression	Ovarian Follicle Development DNA Repair DNA Damage Response Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair
Pathways		Zygotic genome activation (ZGA) Zygotic genome activation (ZGA)	Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases			Fanconi anemia
GWAS			Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		18 interacting genes: ATXN1 FANCG GOLGA2 GOLGA6L9 INCA1 KRTAP19-7 KRTAP6-2 MKRN3 NELFB OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SERTAD3 USHBP1 ZNRF4	44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1
Entrez ID		284355	2189
HPRD ID		13447	04262
Ensembl ID		ENSG00000178928	ENSG00000221829
Uniprot IDs		A0A8V8TMK4 D2CFI5 Q8N7U7	O15287 Q53XM5
PDB IDs			7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
Enriched GO Terms of Interacting Partners?			DNA Metabolic Process DNA Damage Response DNA Repair Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex Mitotic G2 DNA Damage Checkpoint Signaling Telomere Maintenance Via Recombination Mitotic G2/M Transition Checkpoint Mitotic Recombination Nucleic Acid Metabolic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Damage Checkpoint Signaling Female Gonad Development Signal Transduction In Response To DNA Damage Nucleoplasm Nuclear Ubiquitin Ligase Complex Chromosome, Telomeric Region Golgi Disassembly Cellular Response To Stress Telomere Maintenance DNA Damage Checkpoint Signaling Regulation Of Glycoprotein Biosynthetic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-A Complex Chromosome Organization Centrosome Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Double-strand Break Repair Regulation Of Cell Cycle Positive Regulation Of Glutamate Receptor Signaling Pathway Telomere Organization Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Gonad Development Regulation Of Lymphoid Progenitor Cell Differentiation Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Primary Metabolic Process Meiosis I Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Nucleus Cellular Response To Radiation Organelle Organization Regulation Of Embryonic Development Microtubule Organizing Center Organization Chromatin Reproductive Structure Development
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