ZNF148 and POU6F2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF148	POU6F2
Description		zinc finger protein 148	POU class 6 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Chromatin Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Visual Perception
Pathways
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Adult body size ( 32376654) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Caffeine consumption from tea ( 33287642) Feeling hurt ( 29500382) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673) Hand grip strength ( 29691431) Intraocular pressure ( 29785010 30054594 31959993) Motion sickness ( 25628336) Refractive error ( 32231278) Tea consumption ( 31046077)
Interacting Genes		25 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12	143 interacting genes: ACTN3 AIRIM ANKRD10 ARHGEF6 ASB13 BANP BFSP2 BHLHE40 C5 CCHCR1 CCNC CCNK CDC23 CDC37 CDKN2C CHAF1A CIB3 CINP CSNK2A1 CSTF2 CTNNA3 DDX6 DTNB DYDC1 EBF1 EIF3F EIF4EBP1 EPHB6 FHL2 FNDC3B FOSB GCM2 GLIS2 GMEB2 GOLGA6L9 HGS HIVEP1 HNF1B HOXC5 HOXC8 HSPA4 IGFN1 IMPDH2 IQUB IRX4 ISX KDF1 KIF5B KLHL11 KPNA5 KPNA6 KRTAP8-1 L3MBTL2 LARP4 LMNB2 LMO3 LNX1 LONRF1 MAGEA12 MAPK9 MEIS2 MIEN1 MLLT10 MORF4L2 MSRB3 MSX2 MYL7 MYO15B NEUROG3 NFYC NKX3-2 NME7 NUP62CL OAZ3 OIP5 OPLAH OPTN PADI4 PARVG PDE6H PIBF1 PKN1 PM20D2 POLR3C POU2F1 PPIL1 PPIP5K2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RAD23B RBM39 RBPMS RELA SIX1 SMAD5 SMYD1 SORL1 SOX10 SSUH2 STAC STRA8 TBX6 TCEA2 TENT5B THADA THAP1 TLX2 TLX3 TNPO2 TNXB TP53BP1 TRIM73 TRIML2 TSC1 TSEN15 TTC19 TTC23 UBAC1 UFSP1 VAX2 VENTX VEZF1 VPS9D1 XPOT ZBTB24 ZBTB4 ZFHX2 ZFHX3 ZFP1 ZFP91 ZIM2 ZMYND12 ZNF148 ZNF319 ZNF34 ZNF384 ZNF410 ZNF574
Entrez ID		7707	11281
HPRD ID		03540	10162
Ensembl ID		ENSG00000163848	ENSG00000106536
Uniprot IDs		Q9UQR1	A0A6E1XZL4 P78424
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Lineage Commitment De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Negative Regulation Of MiRNA Processing Regulation Of Carbohydrate Catabolic Process Regulation Of Purine Nucleotide Metabolic Process T-helper 17 Cell Lineage Commitment Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of Regulatory NcRNA Processing T-helper Cell Lineage Commitment CD4-positive, Alpha-beta T Cell Lineage Commitment System Development Organelle Organization Histone Acetyltransferase Complex CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process Organelle Assembly Alpha-beta T Cell Lineage Commitment Identical Protein Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing RRNA Transcription Centriole Replication Centriole Assembly Regulation Of Generation Of Precursor Metabolites And Energy Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Peptidyl-lysine Propionylation Nervous System Development Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity RNA Polymerase III Assembly RNA Polymerase I Assembly Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Cell Differentiation Cellular Component Assembly	Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Protein Binding Chromatin Regulation Of Primary Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Pattern Specification Process Negative Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Zinc Ion Binding Transcription Cis-regulatory Region Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Branch Elongation Involved In Ureteric Bud Branching Stem Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Nuclear Import Signal Receptor Activity Animal Organ Development Activation Of Meiosis Nuclear Localization Sequence Binding DNA-templated Transcription
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