REDIC1 and DYNLL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		REDIC1	DYNLL2
Description		regulator of DNA class I crossover intermediates 1	dynein light chain LC8-type 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding
	Biological Process	Meiotic Cell Cycle	Microtubule-based Process
Pathways			Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		5 interacting genes: DYNLL1 DYNLL2 LMO4 NXF1 TNPO2	30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1
Entrez ID		283461	140735
HPRD ID		08806	06489
Ensembl ID		ENSG00000180116	ENSG00000264364
Uniprot IDs		Q86WS4	Q96FJ2
PDB IDs			2XQQ 3P8M 4D07 7CNU
Enriched GO Terms of Interacting Partners?		Cytoplasmic Dynein Complex Dynein Intermediate Chain Binding Dynein Complex Microtubule Associated Complex Ciliary Tip Tertiary Granule Membrane Scaffold Protein Binding Myosin V Complex Phosphatidylserine Exposure On Blood Platelet Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Activation Of Blood Coagulation Via Clotting Cascade Ventral Spinal Cord Interneuron Differentiation Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Calcium Activated Phosphatidylserine Scrambling Positive Regulation Of Potassium Ion Export Across Plasma Membrane Calcium Activated Phospholipid Scrambling Calcium Activated Phosphatidylcholine Scrambling Negative Regulation Of Cell Volume Spinal Cord Motor Neuron Cell Fate Specification Plasma Membrane Bounded Cell Projection Organization Nuclear RNA Export Factor Complex Spinal Cord Association Neuron Differentiation Cell Projection Organization Nitric-oxide Synthase Regulator Activity Intraciliary Retrograde Transport Microtubule Cytoskeleton Negative Regulation Of DNA-templated DNA Replication Nuclear Transport Nucleocytoplasmic Transport Nuclear Inclusion Body Transcription Export Complex 9+0 Non-motile Cilium Calcium-activated Cation Channel Activity Regulation Of Potassium Ion Export Across Plasma Membrane Voltage-gated Monoatomic Ion Channel Activity Voltage-gated Chloride Channel Activity Positive Regulation Of Phagocytosis, Engulfment Bleb Assembly DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Nitric Oxide Biosynthetic Process Microtubule Intracellular Transport Intracellularly Calcium-gated Chloride Channel Activity Protein-containing Complex Binding Plasma Membrane Bounded Cell Projection Assembly	Microtubule Binding
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