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CCL7
Description
C-C motif chemokine ligand 7
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Molecular Function
Cytokine Activity
Protein Binding
Chemokine Activity
Heparin Binding
CCR1 Chemokine Receptor Binding
CCR2 Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Biological Process
Monocyte Chemotaxis
Intracellular Calcium Ion Homeostasis
Chemotaxis
Inflammatory Response
Immune Response
Cytoskeleton Organization
Signal Transduction
Canonical NF-kappaB Signal Transduction
Cell-cell Signaling
Regulation Of Cell Shape
Response To Gamma Radiation
Signal Transduction Involved In Regulation Of Gene Expression
Positive Regulation Of Cell Migration
Eosinophil Chemotaxis
Positive Regulation Of Inflammatory Response
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Ethanol
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways
Chemokine receptors bind chemokines
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Crohn's disease (
21102463
22412388
28067908
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
28067908
)
Novel Interacting Genes
2 novel interacting genes:
AATF
ERBB2
Interacting Genes
18 interacting genes:
ACKR1
ACKR2
ACKR4
CCR1
CCR10
CCR3
CCR5
CXCL6
FEZ1
MMP1
MMP13
MMP14
MMP2
MMP3
TLE5
UBQLN1
UBQLN2
XCL2
Entrez ID
6354
HPRD ID
01150
Ensembl ID
ENSG00000108688
Uniprot IDs
P80098
PDB IDs
1BO0
1NCV
4ZKC
7S58
7S59
7SCU
8FJ3
8FK6
8FK8
8JPS
Enriched GO Terms of Interacting Partners
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Chemokine-mediated Signaling Pathway
C-C Chemokine Binding
Chemokine Receptor Activity
C-C Chemokine Receptor Activity
Cell Chemotaxis
Chemotaxis
Locomotion
Cytokine-mediated Signaling Pathway
Collagen Catabolic Process
Extracellular Matrix Disassembly
Collagen Metabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Migration
Cell Surface Receptor Signaling Pathway
Calcium-mediated Signaling
Endopeptidase Activity
Metalloendopeptidase Activity
Cell Motility
G Protein-coupled Receptor Signaling Pathway
Cellular Response To UV-A
G Protein-coupled Receptor Activity
Metallopeptidase Activity
Response To UV-A
Serine-type Endopeptidase Activity
Chemokine (C-C Motif) Ligand 5 Binding
Inflammatory Response
Immune System Process
External Side Of Plasma Membrane
Immune Response
Response To Stress
Extracellular Structure Organization
Extracellular Matrix Organization
Leukocyte Chemotaxis
Chemokine Binding
Intracellular Signaling Cassette
Response To Amyloid-beta
Defense Response
Extracellular Matrix
Leukocyte Migration
Peptidase Activity
Cellular Response To UV
Signal Transduction
Dendritic Cell Chemotaxis
Positive Regulation Of ERAD Pathway
Mononuclear Cell Migration
Proteolysis
Cellular Response To Light Stimulus
Plasma Membrane
Response To Cytokine
Dendritic Cell Migration
Tagcloud
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