GPD1 and PTN

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPD1	PTN
Description		glycerol-3-phosphate dehydrogenase 1	pleiotrophin
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum Plasma Membrane Protein-containing Complex Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Homodimerization Activity Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity NAD Binding Glycerol-3-phosphate Dehydrogenase (NAD+) Activity	Protein Phosphatase Inhibitor Activity Integrin Binding Protein Binding Growth Factor Activity Heparin Binding Protein Kinase Binding Carbohydrate Binding Chondroitin Sulfate Binding Molecular Function Activator Activity
	Biological Process	Carbohydrate Metabolic Process Glycerol-3-phosphate Metabolic Process Gluconeogenesis Glycerol-3-phosphate Shuttle Positive Regulation Of Glycolytic Process Glycerol-3-phosphate Catabolic Process Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor	Ossification Leukocyte Chemotaxis Involved In Inflammatory Response Positive Regulation Of Leukocyte Chemotaxis Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Integrin-mediated Signaling Pathway Nervous System Development Negative Regulation Of Neuroblast Proliferation Learning Memory Positive Regulation Of Cell Population Proliferation Regulation Of Endothelial Cell Migration Positive Regulation Of Neuron Projection Development Response To Auditory Stimulus Bone Mineralization Positive Regulation Of Bone Mineralization Dendrite Regeneration Regulation Of Myelination Tissue Regeneration Receptor Clustering Ossification Involved In Bone Remodeling Estrous Cycle Positive Regulation Of Cell Differentiation Positive Regulation Of Ossification Decidualization Regulation Of Synaptic Plasticity Oogenesis Positive Regulation Of Axon Regeneration Positive Regulation Of Oligodendrocyte Differentiation Modulation Of Chemical Synaptic Transmission Positive Regulation Of Cell Division Dendrite Arborization Positive Regulation Of Dendrite Development Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Hemopoiesis Regulation Of Stem Cell Population Maintenance Positive Regulation Of Hepatocyte Proliferation Positive Regulation Of Stem Cell Differentiation
Pathways		Synthesis of PA	Signaling by ALK Signaling by ALK MDK and PTN in ALK signaling MDK and PTN in ALK signaling
Drugs		NADH Metformin
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Hip circumference adjusted for BMI ( 34021172)	Aluminium levels ( 26025379) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 30072576) Metabolite levels ( 23823483) Neurociticism ( 29500382) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia ( 25056061 29483656)
Interacting Genes		7 interacting genes: FAM25A FAM25C FAM25G GK MDH1 POMP PTN	101 interacting genes: ACTB ALK APOBEC3G ARIH2 ARL15 ASPH ATP5F1C ATRX BAG6 BARD1 BCCIP BCL2L1 BLOC1S1 BMI1 BTBD2 C11orf58 C7orf25 CAAP1 CACNB4 CAPZB CDH10 CDK5RAP2 CGA CHD3 COX6C CRCT1 CRELD1 CSTA CYP2E1 DNAJB11 DUSP12 EIF3F EVA1A FEZ1 FTL GADD45A GADD45G GIPC2 GLYAT GPD1 GPRASP2 GSDME GSK3B GSTP1 GTF2F1 HGH1 HSPBAP1 ITSN2 KPNB1 LAMA4 LUC7L2 MAD2L1BP MFRP MKKS MLLT3 MRPL44 MYCBP NAP1L5 NCAN NEK6 NUDT21 P4HB PFDN1 PIAS4 PLXNB2 PMF1 PPP2CA PSMB10 PSMD11 PSMD2 PTPRS PTPRZ1 RACK1 RBM23 RIT1 RNF167 ROR1 RPLP1 SAT1 SDC1 SDC3 SGSM2 SGTA SLC25A36 SNCAIP SPIN1 SSR1 STC2 SUPT7L TAC3 TAF1D TBRG4 TOMM20 TP53BP2 TSC22D1 TXNDC9 UBQLN1 UBQLN4 UTP3 WASHC3 WFDC2
Entrez ID		2819	5764
HPRD ID		00714	01199
Ensembl ID		ENSG00000167588	ENSG00000105894
Uniprot IDs		A0A024R138 P21695	A0A8V8TNI1 P21246
PDB IDs		1WPQ 1X0V 1X0X 6E8Y 6E8Z 6E90 6PYP	2N6F 8VOH 8VOI
Enriched GO Terms of Interacting Partners?		Glycerol Kinase Activity Glycerol-3-phosphate Biosynthetic Process Intermediate Filament Polymerization Diiodophenylpyruvate Reductase (NAD+) Activity (2R)-hydroxyphenylpyruvate Reductase [NAD(P)H] Activity Intermediate Filament Polymerization Or Depolymerization Dendrite Regeneration L-malate Dehydrogenase (NAD+) Activity Malate Dehydrogenase Activity Ossification Involved In Bone Remodeling Glycerol Catabolic Process Glycerol-3-phosphate Metabolic Process Malic Enzyme Activity	Regulation Of Cellular Response To Stress
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