GPD1 and POMP

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		GPD1	POMP
Description		glycerol-3-phosphate dehydrogenase 1	proteasome maturation protein
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Nuclear Speck
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Homodimerization Activity Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity NAD Binding Glycerol-3-phosphate Dehydrogenase (NAD+) Activity	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Glycerol-3-phosphate Metabolic Process Gluconeogenesis Glycerol-3-phosphate Shuttle Positive Regulation Of Glycolytic Process Glycerol-3-phosphate Catabolic Process Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor	Proteasome Assembly
Pathways		Synthesis of PA	Proteasome assembly Proteasome assembly
Drugs		NADH Metformin
Diseases			Keratosis linearis with ichthyosis congenita and sclerosing keratoderma; KLICK syndrome
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Hip circumference adjusted for BMI ( 34021172)	Breast cancer (menopausal hormone therapy interaction) ( 24080446) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: FAM25A FAM25C FAM25G GK MDH1 POMP PTN	24 interacting genes: ATXN1 CAPN3 DCPH1 ECT2 FAM107A GPD1 GRB2 KCNA10 KIF1B KLHL41 MPPED2 PSMA3 PSMB1 PSMB10 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PYGM RBM5 SSR4 TTN VCL
Entrez ID		2819	51371
HPRD ID		00714	12613
Ensembl ID		ENSG00000167588	ENSG00000132963
Uniprot IDs		A0A024R138 P21695	Q9Y244
PDB IDs		1WPQ 1X0V 1X0X 6E8Y 6E8Z 6E90 6PYP	8QYJ 8QYL 8QYM 8QYN 8QYS 8QZ9 8TM4 8TM5 8TM6 8YIX 8YIY
Enriched GO Terms of Interacting Partners?		Glycerol Kinase Activity Glycerol-3-phosphate Biosynthetic Process Intermediate Filament Polymerization Diiodophenylpyruvate Reductase (NAD+) Activity (2R)-hydroxyphenylpyruvate Reductase [NAD(P)H] Activity Intermediate Filament Polymerization Or Depolymerization Dendrite Regeneration L-malate Dehydrogenase (NAD+) Activity Malate Dehydrogenase Activity Ossification Involved In Bone Remodeling Glycerol Catabolic Process Glycerol-3-phosphate Metabolic Process Malic Enzyme Activity	Proteasome Core Complex Proteasome Core Complex, Beta-subunit Complex Threonine-type Endopeptidase Activity Proteasome Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Endopeptidase Activity Protein Catabolic Process Proteasomal Protein Catabolic Process Spermatoproteasome Complex Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process Peptidase Activity Proteolysis Catabolic Process Extracellular Exosome Myofibril Assembly Cytosol Cytoplasm Hydrolase Activity Actomyosin Structure Organization M Band Secretory Granule Lumen Ficolin-1-rich Granule Lumen Response To Calcium Ion Insulin-like Growth Factor Receptor Signaling Pathway Calcium-dependent Self Proteolysis Protein-containing Complex Assembly Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Guanyl-nucleotide Exchange Factor Adaptor Activity Inner Dense Plaque Of Desmosome Podosome Ring Outer Dense Plaque Of Desmosome Protein Carboxyl O-methyltransferase Activity Protein-glutamate O-methyltransferase Activity Fructose 6-phosphate Aldolase Activity Actin Cytoskeleton Organization Sarcomere Organization Structural Constituent Of Muscle Myofibril Actin Filament-based Process Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Protein-containing Complex Organization Cell-cell Junction Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle
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