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TLE5 and GFAP
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
TLE5
GFAP
Description
TLE family member 5, transcriptional modulator
glial fibrillary acidic protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Lysosome
Cytosol
Cytoskeleton
Intermediate Filament
Membrane
Cell Projection
Cell Body
Intermediate Filament Cytoskeleton
Glial Cell Projection
Astrocyte Projection
Astrocyte End-foot
Cytoplasmic Side Of Lysosomal Membrane
Molecular Function
Transcription Corepressor Activity
Protein Binding
Identical Protein Binding
Integrin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Kinase Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Gene Expression
Wnt Signaling Pathway
Regulation Of Growth
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Response To Cytokine Stimulus
Response To Interleukin-1
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Anoikis
Intracellular Protein Transport
Gene Expression
Positive Regulation Of Schwann Cell Proliferation
Negative Regulation Of Neuron Projection Development
Astrocyte Development
Schwann Cell Proliferation
Extracellular Matrix Organization
Neuron Projection Regeneration
Neuron Projection Development
Regulation Of Protein-containing Complex Assembly
Intermediate Filament-based Process
Intermediate Filament Organization
Regulation Of Neurotransmitter Uptake
Bergmann Glial Cell Differentiation
Positive Regulation Of Glial Cell Proliferation
Long-term Synaptic Potentiation
D-aspartate Import Across Plasma Membrane
Regulation Of Chaperone-mediated Autophagy
Pathways
Repression of WNT target genes
Nuclear signaling by ERBB4
Chaperone Mediated Autophagy
Drugs
Diseases
Alexander disease
GWAS
Asthma (
31619474
)
Cognitive function (
25644384
)
Craniofacial microsomia (
26853712
)
Interacting Genes
363 interacting genes:
ABI2
ACTMAP
AEN
AGR2
AIRIM
AKAP8L
ANAPC11
ANKRD11
AR
ARHGAP32
ARX
ASB3
ATN1
ATOSB
ATP6V0D1
BAG4
BAHD1
BCL6
BHLHE40
BIRC7
BPIFA1
BYSL
C10orf55
C14orf119
C1orf216
C1orf94
C7orf57
CABP2
CABP4
CABP5
CALCOCO2
CAPN1
CARD9
CATSPERT
CCDC120
CCDC57
CCL7
CCNJL
CCNK
CFAP206
CFAP68
CIB3
CLIC3
CLIP3
CNFN
COA7
CPSF7
CRACR2A
CSNK1E
CSNK2A1
CSTF2
CSTF2T
CT55
CTBP2
CYSRT1
DAZAP2
DCUN1D1
DDX6
DGCR6
DIP2A
DMRT2
DMRT3
DMRTB1
DNMT3L
DOK6
DVL2
DVL3
DYDC1
EAF1
EAF2
EFEMP2
EFHC1
EIF1AD
EIF4E2
ERF
EXOSC5
EYA2
FAM124A
FAM124B
FAM168B
FAM217B
FAM90A1
FANCG
FBF1
FCHSD2
FHL3
FOSB
FOXD2
FOXN1
FOXP2
FRS3
FSD2
FXR1
FXR2
GABARAP
GATA1
GCC1
GEM
GFAP
GFI1B
GIGYF1
GLIS2
GLRX3
GOLGA2
GOLGA6L9
GORASP2
GPANK1
GPATCH2L
GRAP2
GRB2
GRN
GTF2E1
GYS1
HDAC4
HDHD3
HELT
HEXIM2
HGS
HHEX
HMGB1
HNF1A
HNRNPF
HNRNPH2
HNRNPK
HNRNPLL
HOMEZ
HOXA1
HOXB5
HOXC8
HOXC9
IKZF3
INO80B
INO80E
INPP5J
IRX2
IRX6
KANK2
KDM1A
KIFC3
KLF1
KLF4
KLHDC7B
KRT13
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP10-11
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP13-2
KRTAP13-3
KRTAP17-1
KRTAP19-5
KRTAP19-7
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
L3MBTL2
LDLR
LDOC1
LENG8
LINC00526
LMO1
LMO2
LMO4
LSM2
LZTS2
MAGOHB
MAPK1
MAPK14
MAPRE3
MBNL1
MCRS1
MDFI
MECOM
MED12L
MED25
MED31
MED4
MEIS3
MFAP1
MIA2
MIIP
MKRN3
MLH1
MLLT6
MLX
MORF4L1
MORF4L2
MSS51
MSX1
MSX2
MTUS2
MVP
MYF5
MYH7B
MYO15B
MYOG
NAB2
NAF1
NBPF19
NCDN
NDOR1
NDUFB7
NEK6
NLGN3
NOTCH2NLA
NTAQ1
NUDT22
NUTF2
NUTM1
OLIG3
OSGIN1
OXER1
P4HA3
PARVG
PATZ1
PCBP1
PCSK5
PFDN5
PHF1
PICK1
PITX1
PITX2
PLAGL1
POLR1C
POU2F1
PPP1R16A
PPP1R16B
PRDM1
PRDM14
PRDM6
PRKAA1
PRKAA2
PRKAB2
PROP1
PRPF31
PRR3
PRR35
PSMB1
PSMB4
PSMF1
PTRH2
QARS1
RAD51D
RBM10
RBPMS
REL
RELA
RFX6
RHOXF2
RIBC1
RIMBP3
RNF31
RORB
RPL18A
RUNX1
RUSC1
SAT1
SCNM1
SDCBP
SERTAD3
SET
SF3B4
SH2B2
SH3GL3
SHFL
SHISA6
SIX1
SIX2
SIX3
SIX6
SKIL
SKP2
SMAD3
SMAD4
SMARCB1
SMARCD1
SNCAIP
SNRPA
SNRPC
SOHLH1
SPATA25
SPG21
SPMIP9
SRPK2
SSC4D
STK16
STX11
SUFU
SUPT5H
TBX3
TBX6
TCEANC
TCF4
TCF7L2
TEAD4
TENT5B
TFAP2D
THAP7
TIGD3
TMCC2
TNS2
TOX3
TRAF1
TRAF2
TRIB3
TRIM26
TRIM27
TRIM41
TRIP6
TRMT2A
TSC1
TSC22D4
TSEN15
TSGA10
TSGA10IP
TSSK3
TTC23
U2AF2
UBAP2
UBE2H
UBL5
UBXN11
USP2
USP54
VEZF1
VGLL1
VIM
VPS37B
VPS37C
YPEL3
YTHDF1
ZBTB16
ZBTB24
ZBTB47
ZFHX3
ZGPAT
ZIC1
ZMYND12
ZNF330
ZNF34
ZNF383
ZNF408
ZNF414
ZNF417
ZNF467
ZNF48
ZNF503
ZNF524
ZNF576
ZNF688
ZNF792
ZNF835
ZRANB1
86 interacting genes:
ABI2
AKT1
APP
AURKB
BIRC2
CAMK2A
CARD10
CCDC57
CDC37
CDK1
CEP76
CFAP206
CRYAB
CT55
CWF19L2
DSCAM
ENKD1
EPM2AIP1
FAM50B
FXR1
FXR2
GOLGA2
GRAP2
HGS
HOMEZ
IKBKG
ITSN1
KIAA0408
KRT13
KRT15
KRT19
KRT27
KRT31
KRT39
LENG1
LGALS14
LMO2
MAPK9
MEN1
MOS
MYBPHL
MYO15B
NEFL
NEIL3
NEK6
NFKBID
NTAQ1
NXF1
PDLIM1
PDLIM7
PDZK1
PIAS2
PIH1D2
POM121
PPP1R16B
PPP1R18
PRKACA
PRKCA
PRKCG
PSEN1
PSEN2
RIBC2
ROCK1
RORA
S100A1
S100B
SH3YL1
SMARCA2
SMARCB1
SRC
STAT1
TBC1D21
TBC1D22B
TFIP11
TLE5
TP53BP2
TRIM27
TSC1
TUBGCP4
UBASH3A
UBE3A
VIM
YES1
ZC2HC1C
ZNF655
ZNF774
Entrez ID
166
2670
HPRD ID
02556
00675
Ensembl ID
ENSG00000104964
ENSG00000131095
Uniprot IDs
Q08117
A0A1X7SBR3
P14136
PDB IDs
6A9P
Enriched GO Terms of Interacting Partners
?
Protein Binding
Regulation Of RNA Metabolic Process
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Negative Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin
Positive Regulation Of RNA Metabolic Process
DNA-binding Transcription Factor Activity
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Intermediate Filament
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
DNA Binding
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Nucleoplasm
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Metabolic Process
Transcription Regulator Complex
Negative Regulation Of Macromolecule Biosynthetic Process
Sequence-specific DNA Binding
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Sequence-specific Double-stranded DNA Binding
Negative Regulation Of Metabolic Process
Keratin Filament
Identical Protein Binding
Transcription Cis-regulatory Region Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Transcription Corepressor Binding
Cellular Developmental Process
Cell Differentiation
Pattern Specification Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Cytoskeleton Organization
Intermediate Filament Organization
Cytoskeleton
Supramolecular Fiber Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Protein Binding
Protein Serine/threonine/tyrosine Kinase Activity
Intracellular Signal Transduction
Structural Constituent Of Skin Epidermis
Cytoplasm
Protein Kinase Activity
Intermediate Filament
Protein Serine Kinase Activity
Regulation Of Cellular Component Organization
Microtubule Cytoskeleton Organization
Organelle Organization
Response To Peptide Hormone
Positive Regulation Of Signaling
Regulation Of Generation Of Precursor Metabolites And Energy
Protein Serine/threonine Kinase Activity
Protein-containing Complex
Keratin Filament
Regulation Of Synaptic Plasticity
Protein Phosphorylation
Nucleus
Kinase Activity
Regulation Of Neuronal Synaptic Plasticity
Structural Constituent Of Cytoskeleton
Response To Hormone
Regulation Of Protein Metabolic Process
Positive Regulation Of Cell Communication
Cytosol
Regulation Of Sister Chromatid Segregation
Regulation Of Cell Cycle
Regulation Of Apoptotic Process
Synaptic Membrane
Mitotic Nuclear Membrane Disassembly
Developmental Process
Negative Regulation Of TORC1 Signaling
Intracellular Signaling Cassette
Regulation Of Proteolysis
Phosphorylation
Regulation Of Circadian Rhythm
Regulation Of Signaling
Positive Regulation Of Gene Expression
Regulation Of Cell Communication
Regulation Of Programmed Cell Death
Positive Regulation Of Signal Transduction
Structural Molecule Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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