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GLI2 and STK36
Number of citations of the paper that reports this interaction (PMID
10806483
)
26
Data Source:
HPRD
(in vivo)
GLI2
STK36
Gene Name
GLI family zinc finger 2
serine/threonine kinase 36
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Membrane
Nuclear Speck
Motile Primary Cilium
Ciliary Tip
Ciliary Base
Nucleus
Cytoplasm
Molecular Function
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Skeletal System Development
Osteoblast Differentiation
In Utero Embryonic Development
Kidney Development
Chondrocyte Differentiation
Osteoblast Development
Transcription, DNA-templated
Smoothened Signaling Pathway
Pattern Specification Process
Axon Guidance
Ventral Midline Development
Hindgut Morphogenesis
Heart Development
Cell Proliferation
Regulation Of Smoothened Signaling Pathway
Response To Mechanical Stimulus
Epidermal Cell Differentiation
Proximal/distal Pattern Formation
Floor Plate Formation
Spinal Cord Dorsal/ventral Patterning
Ventral Spinal Cord Development
Cerebellar Cortex Morphogenesis
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Regulation Of Cerebellar Granule Cell Precursor Cell Proliferation
Spinal Cord Ventral Commissure Morphogenesis
Pituitary Gland Development
Lung Development
Mammary Gland Development
Hindbrain Development
Negative Regulation Of Chondrocyte Differentiation
Positive Regulation Of T Cell Differentiation In Thymus
Tube Development
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Positive Regulation Of Neuron Differentiation
Positive Regulation Of DNA Replication
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Embryonic Digestive Tract Development
Developmental Growth
Neuron Development
Branching Morphogenesis Of An Epithelial Tube
Notochord Regression
Prostatic Bud Formation
Mammary Gland Duct Morphogenesis
Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Cellular Response To Organic Cyclic Compound
Cochlea Morphogenesis
Cellular Response To Virus
Epithelial Cilium Movement
Protein Phosphorylation
Positive Regulation Of Hh Target Transcription Factor Activity
Brain Development
Post-embryonic Development
Cilium Assembly
Positive Regulation Of Smoothened Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
Hedgehog 'off' state
Hedgehog 'on' state
Signaling by Hedgehog
GLI proteins bind promoters of Hh responsive genes to promote transcription
Degradation of GLI2 by the proteasome
Drugs
Diseases
GWAS
Age-related macular degeneration (
23326517
)
Breast size (
22747683
)
Erectile dysfunction and prostate cancer treatment (
20932654
)
Amyotrophic lateral sclerosis (
22959728
)
Protein-Protein Interactions
7 interactors:
CREB1
FBXW11
SKI
STK36
SUFU
ZIC1
ZIC2
9 interactors:
CDK5RAP2
CDK9
FRMPD4
GLI1
GLI2
GLI3
MAST2
MID1
SUFU
Entrez ID
2736
27148
HPRD ID
01312
09631
Ensembl ID
ENSG00000074047
ENSG00000163482
Uniprot IDs
P10070
Q1PSW9
Q59FV5
Q9NRP7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Central Nervous System Development
Brain Development
Head Development
Regulation Of Smoothened Signaling Pathway
Neural Tube Closure
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Neural Tube Formation
Nervous System Development
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Anatomical Structure Morphogenesis
Regulation Of RNA Biosynthetic Process
Embryonic Epithelial Tube Formation
Epithelial Tube Formation
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Tube Formation
Regulation Of Protein Import Into Nucleus
Morphogenesis Of Embryonic Epithelium
Regulation Of Gene Expression
Embryonic Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Neural Tube Development
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Nucleocytoplasmic Transport
Tube Development
Organ Development
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Signaling
Regulation Of Intracellular Protein Transport
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cellular Localization
Anatomical Structure Formation Involved In Morphogenesis
Epithelium Development
Epithelial Tube Morphogenesis
Embryo Development
System Development
Negative Regulation Of Protein Import Into Nucleus
Tube Morphogenesis
Regulation Of Intracellular Transport
Negative Regulation Of Ossification
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Ventral Spinal Cord Interneuron Specification
Spinal Cord Motor Neuron Cell Fate Specification
Ventral Spinal Cord Interneuron Fate Commitment
Regulation Of Smoothened Signaling Pathway
Ventral Spinal Cord Interneuron Differentiation
Smoothened Signaling Pathway
Dorsal/ventral Pattern Formation
Notochord Regression
Spinal Cord Dorsal/ventral Patterning
Neuron Fate Specification
Spinal Cord Patterning
Pattern Specification Process
Spinal Cord Motor Neuron Differentiation
Proximal/distal Pattern Formation
Smoothened Signaling Pathway Involved In Regulation Of Cerebellar Granule Cell Precursor Cell Proliferation
Ventral Midline Development
Positive Regulation Of Neural Precursor Cell Proliferation
Ventral Spinal Cord Development
Cell Differentiation In Spinal Cord
Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation
Digestive Tract Morphogenesis
Neuron Fate Commitment
Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation
Embryonic Organ Morphogenesis
Hindgut Morphogenesis
Notochord Morphogenesis
Cell Fate Specification
Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Hindgut Development
Regulation Of Neural Precursor Cell Proliferation
Spinal Cord Development
Regulation Of DNA Replication
Tube Morphogenesis
Central Nervous System Development
Anatomical Structure Regression
Digestive Tract Development
Digestive System Development
Embryonic Organ Development
Notochord Development
Neural Tube Development
Positive Regulation Of Transcription, DNA-templated
Embryonic Morphogenesis
Central Nervous System Neuron Differentiation
Negative Regulation Of Smoothened Signaling Pathway
Dorsal/ventral Neural Tube Patterning
Tube Development
Lung Development
Tagcloud
?
activates
bcar4
ccl21
chemokine
consequences
consisting
coordinated
correlates
enables
extended
h3k18ac
hedgehog
indirect
lnas
lncrna
lncrnas
locked
noncanonical
nucleic
pnuts
pol
pp1
recruited
releases
relieve
snip1
suppresses
tumorigenic
turn
Tagcloud (Difference)
?
activates
bcar4
ccl21
chemokine
consequences
consisting
coordinated
correlates
enables
extended
h3k18ac
hedgehog
indirect
lnas
lncrna
lncrnas
locked
noncanonical
nucleic
pnuts
pol
pp1
recruited
releases
relieve
snip1
suppresses
tumorigenic
turn
Tagcloud (Intersection)
?