HTATSF1 and FEZ1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HTATSF1	FEZ1
Description		HIV-1 Tat specific factor 1	fasciculation and elongation protein zeta 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Chromosome Site Of Double-strand Break	Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Microtubule Plasma Membrane Membrane Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Chromatin-protein Adaptor Activity Poly-ADP-D-ribose Modification-dependent Protein Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination DNA Repair Chromatin Organization MRNA Processing DNA Damage Response RNA Splicing U2-type Prespliceosome Assembly Protein Localization To Site Of Double-strand Break	Mitochondrion Organization Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		21 interacting genes: APBB1 CCNT1 CDK9 CLK1 CSNK2A1 ERCC6 FEZ1 GTF2F2 HDAC6 MAP1LC3A POLR2A RNF10 SF3A2 SNRNP70 SNRPB2 SRPK2 SRSF4 SUPT4H1 SUPT5H WBP4 ZNF512B	60 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 DYRK1A FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 NRIP1 OLFML3 P4HB PAM16 PCNT PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		27336	9638
HPRD ID		02282	09212
Ensembl ID		ENSG00000102241	ENSG00000149557
Uniprot IDs		O43719	Q99689
PDB IDs		2DIT 6N3D 6N3E 6N3F 6NSX 6Y50 6Y53 6Y5Q 7EVO 7Q3L 8HK1
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process DNA-templated Transcription Elongation Nucleic Acid Metabolic Process Transcription Elongation By RNA Polymerase II Nucleoplasm Positive Regulation Of DNA-templated Transcription, Elongation Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Elongation Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Nuclear Speck Regulation Of Gene Expression P-TEFb Complex DSIF Complex Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Splicing Negative Regulation Of DNA-templated Transcription, Elongation RNA Splicing RNA Splicing, Via Transesterification Reactions Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Metabolic Process DNA-templated Transcription MRNA Processing Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of MRNA Processing Transcription By RNA Polymerase II Spliceosomal Complex Assembly Transcription Elongation-coupled Chromatin Remodeling U2-type Precatalytic Spliceosome Negative Regulation Of Metabolic Process Cyclin/CDK Positive Transcription Elongation Factor Complex U1 SnRNA Binding Positive Regulation Of Transcription Elongation By RNA Polymerase II 7SK SnRNA Binding Nucleic Acid Binding Positive Regulation Of Metabolic Process Spliceosomal Complex Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Autophagy Positive Regulation Of Transcription By RNA Polymerase II SnRNA Binding	Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Autophagosome Microtubule Cytoskeleton Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Response To Stress Centrosome Regulation Of Macroautophagy Microtubule Cytoskeleton Organization Involved In Mitosis Microtubule-based Process Positive Regulation Of Protein Lipidation Cytoskeleton Regulation Of Endoplasmic Reticulum Tubular Network Organization RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of Protein Lipidation Regulation Of Organelle Assembly Regulation Of Microtubule-based Process RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Macroautophagy Positive Regulation Of Organelle Assembly Regulation Of Autophagy Microtubule Organizing Center Mitotic Spindle Organization Axon Negative Regulation Of Microtubule Polymerization Or Depolymerization Chondroitin Sulfate Binding Regulation Of Autophagosome Assembly Regulation Of Organelle Organization
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