BMP10 and BSND

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BMP10	BSND
Description		bone morphogenetic protein 10	barttin CLCNK type accessory subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity
	Biological Process	Kidney Development Cell Adhesion Heart Development Adult Heart Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Multicellular Organismal Process Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	Chloride Transport Sensory Perception Of Sound Chloride Transmembrane Transport
Pathways		Signaling by BMP Molecules associated with elastic fibres	Stimuli-sensing channels
Drugs
Diseases			Bartter syndrome
GWAS		Chronic rhinosinusitis ( 33393196)	Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)
Interacting Genes		61 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CPLX4 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 HSD17B13 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35H1 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR	28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1
Entrez ID		27302	7809
HPRD ID		09788	05914
Ensembl ID		ENSG00000163217	ENSG00000162399
Uniprot IDs		O95393	Q5VU50 Q8WZ55
PDB IDs		6SF1 6SF3 7PPA 7PPB 7PPC 9DPY
Enriched GO Terms of Interacting Partners?		Membrane Activin Receptor Activity, Type II Protein Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Plasma Membrane Activin Receptor Activity Venous Blood Vessel Development Bile Acid:sodium Symporter Activity Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Signaling Pathway Activin Receptor Complex Lymphatic Endothelial Cell Differentiation Fc-gamma Receptor Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway BMP Receptor Activity	Amyloid-beta Complex Lipoprotein Metabolic Process Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Recycling Endosome Trans-Golgi Network Membrane Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To Cytokine Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum Locomotory Behavior Response To CAMP Golgi Apparatus Endoplasmic Reticulum Lumen Positive Regulation Of CAMP/PKA Signal Transduction Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Extracellular Matrix Structural Constituent Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of Cellular Localization Mitochondrial MRNA Processing Regulation Of Hormone Secretion Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Response To Glucose Positive Regulation Of Glycogen (starch) Synthase Activity Response To Monosaccharide Phosphatidylinositol-4-phosphate Binding Amide Transport Intermembrane Sphingolipid Transfer CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi Peroxynitrite Isomerase Activity Insulin Metabolic Process Early Endosome Negative Regulation Of Secretion By Cell Regulation Of System Process
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