BSND and GAD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BSND	GAD2
Description		barttin CLCNK type accessory subunit beta	glutamate decarboxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Axon Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity	Glutamate Decarboxylase Activity Protein Binding Lyase Activity Carbon-carbon Lyase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding
	Biological Process	Chloride Transport Sensory Perception Of Sound Chloride Transmembrane Transport	Gamma-aminobutyrate Shunt Chemical Synaptic Transmission Gamma-aminobutyric Acid Biosynthetic Process Carboxylic Acid Metabolic Process
Pathways		Stimuli-sensing channels	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal phosphate Glutamic acid
Diseases		Bartter syndrome
GWAS		Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)	Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Lean body mass ( 28552196)
Interacting Genes		28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1	48 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BASP1 BSND CACNG1 CALM1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A FTCD GAD1 HIGD1C LDAF1 LIME1 MAL2 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TNFRSF10D TSPAN33
Entrez ID		7809	2572
HPRD ID		05914	11817
Ensembl ID		ENSG00000162399	ENSG00000136750
Uniprot IDs		Q5VU50 Q8WZ55	Q05329 Q5VZ30
PDB IDs			1ES0 2OKK 7LZ6
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Lipoprotein Metabolic Process Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Recycling Endosome Trans-Golgi Network Membrane Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To Cytokine Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum Locomotory Behavior Response To CAMP Golgi Apparatus Endoplasmic Reticulum Lumen Positive Regulation Of CAMP/PKA Signal Transduction Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Extracellular Matrix Structural Constituent Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of Cellular Localization Mitochondrial MRNA Processing Regulation Of Hormone Secretion Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Response To Glucose Positive Regulation Of Glycogen (starch) Synthase Activity Response To Monosaccharide Phosphatidylinositol-4-phosphate Binding Amide Transport Intermembrane Sphingolipid Transfer CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi Peroxynitrite Isomerase Activity Insulin Metabolic Process Early Endosome Negative Regulation Of Secretion By Cell Regulation Of System Process	Membrane Lipid Droplet Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Lipid Catabolic Process Regulation Of Calcium Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Protein Binding Positive Regulation Of Triglyceride Catabolic Process Signal Recognition Particle Binding Substantia Nigra Development Endoplasmic Reticulum Regulation Of Lipid Storage Regulation Of Calcium Ion Transport
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