BMP10 and FNDC9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BMP10	FNDC9
Description		bone morphogenetic protein 10	fibronectin type III domain containing 9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc	Membrane
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding	Protein Binding
	Biological Process	Kidney Development Cell Adhesion Heart Development Adult Heart Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Multicellular Organismal Process Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways		Signaling by BMP Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Chronic rhinosinusitis ( 33393196)	Asthma ( 31959851)
Interacting Genes		61 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CPLX4 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 HSD17B13 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35H1 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR	88 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 AQP1 ASGR1 ATXN1 BMP10 C1QL4 C3orf52 CLDN1 CLDN11 CLDN19 CLEC1A CLEC2D CLEC7A CLN6 CLRN2 CMTM5 CNIH3 COL8A2 CTSA CXCL16 CXCL9 CYB5B DEFB132 DOLK EDDM3B EMP3 ENTPD3 ERMP1 EXTL1 GALNT15 GCNT2 HHATL IGFBP5 ITM2A ITM2C JAGN1 KRTCAP3 LHFPL5 LPAR3 MAL MALL MOSPD3 NINJ1 NINJ2 NKG7 NSG1 OLFM4 PGA4 PGAP2 PLLP PLN PLP1 PLP2 PLPP6 PROKR2 RPRM SEC22B SERP2 SFTPC SLC35A1 SLC41A2 SMIM1 SMIM3 ST6GAL2 STX8 TMEM100 TMEM140 TMEM182 TMEM254 TMEM60 TMEM79 TMEM86A TMPRSS4 TNF TRARG1 TREX1 TSPO2 TWSG1 UBIAD1 UPK1B UPK2 VAMP5 VSTM1 ZDHHC22 ZFPL1
Entrez ID		27302	408263
HPRD ID		09788	17524
Ensembl ID		ENSG00000163217	ENSG00000172568
Uniprot IDs		O95393	Q8TBE3
PDB IDs		6SF1 6SF3 7PPA 7PPB 7PPC 9DPY
Enriched GO Terms of Interacting Partners?		Membrane Activin Receptor Activity, Type II Protein Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Plasma Membrane Activin Receptor Activity Venous Blood Vessel Development Bile Acid:sodium Symporter Activity Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Signaling Pathway Activin Receptor Complex Lymphatic Endothelial Cell Differentiation Fc-gamma Receptor Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway BMP Receptor Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Structural Constituent Of Myelin Sheath Plasma Membrane Protein Binding Positive Regulation Of Neutrophil Activation Golgi Apparatus Axon Ensheathment Cytokine Activity Membrane Destabilizing Activity Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Localization To Cell Periphery
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