AHDC1 and DOK5

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		AHDC1	DOK5
Description		AT-hook DNA binding motif containing 1	docking protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome	Cytoplasm Cytosol
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Promoter-enhancer Loop Anchoring Activity	Protein Binding
	Biological Process	Mesoderm Formation Regulation Of DNA-templated Transcription Cell Differentiation Skin Morphogenesis	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Differentiation Positive Regulation Of MAPK Cascade Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Pathways			RET signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Myocardial infarction ( 33532862) Pulse pressure ( 30578418)	Celiac disease ( 23936387) Erectile dysfunction ( 30583798) Functional MRI ( 20215924) HDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		9 interacting genes: APP ATXN1 DAPK1 DOK5 H3-4 ITSN2 LRRK2 MFHAS1 ZDHHC17	20 interacting genes: AHDC1 ATF3 BNIP3L CCDC85B CDCA4 DOK3 EGFR FANCG IGF1R INSR NTRK2 NTRK3 OLIG1 OPRM1 PFDN5 RAI2 RET SCOC TSC1 WIZ
Entrez ID		27245	55816
HPRD ID		10885	16317
Ensembl ID		ENSG00000126705	ENSG00000101134
Uniprot IDs		Q5TGY3	Q9P104
PDB IDs			1J0W
Enriched GO Terms of Interacting Partners?		Cellular Response To Manganese Ion Regulation Of MAPK Cascade Regulation Of Neurotrophin TRK Receptor Signaling Pathway Golgi-associated Vesicle Positive Regulation Of MAPK Cascade Cellular Response To Catecholamine Stimulus Response To Catecholamine Response To Manganese Ion Syntaxin-1 Binding Locomotory Behavior Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Toll-like Receptor Signaling Pathway Postsynapse Negative Regulation Of Protein Localization To Nucleus Amyloid-beta Complex Cell Projection Morphogenesis Growth Cone Lamellipodium Regulation Of Synapse Organization Visual Behavior Regulation Of Response To Calcium Ion Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Neuron Projection Morphogenesis Positive Regulation Of Toll Signaling Pathway Visual Learning Regulation Of CAMP/PKA Signal Transduction Regulation Of Cell Communication Modulation Of Excitatory Postsynaptic Potential Regulation Of Signaling DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Excitatory Postsynaptic Potential Regulation Of Macrophage Activation Perforant Pathway To Dendrate Granule Cell Synapse Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Positive Regulation Of Signal Transduction GTP Binding Acetylcholine Receptor Activator Activity Adult Locomotory Behavior Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Inflammatory Response Regulation Of Calcium-mediated Signaling	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Insulin Receptor Activity Axon Regulation Of Metabolic Process Enzyme-linked Receptor Protein Signaling Pathway Insulin Receptor Complex Neurotrophin Receptor Activity Neurotrophin Binding Insulin Binding Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Kinase Activity Dendritic Spine Maintenance Action Potential Propagation Neuronal Action Potential Propagation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Insulin-like Growth Factor I Binding Insulin Receptor Substrate Binding Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Endosome Phosphatidylinositol 3-kinase Binding Myelination Axon Ensheathment Myelination In Peripheral Nervous System Learning Or Memory Positive Regulation Of Cell Junction Assembly Cellular Response To Growth Factor Stimulus Endosome Membrane Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Nervous System Process Protein Autophosphorylation Amyloid-beta Clearance Mechanoreceptor Differentiation Cognition Positive Regulation Of Cell Motility Response To Growth Factor Positive Regulation Of Cell Population Proliferation Neurotrophin Signaling Pathway Positive Regulation Of Locomotion
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