VPS4A and CHMP1B

Number of citations of the paper that reports this interaction (PubMedID 11559748)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		VPS4A	CHMP1B
Description		vacuolar protein sorting 4 homolog A	charged multivesicular body protein 1B
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nuclear Pore Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Endosome Membrane Membrane Midbody Late Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Flemming Body ATPase Complex	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Nucleoplasm Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Membrane Coat Midbody Late Endosome Membrane Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Protein-containing Complex Binding ATP-dependent Protein Disaggregase Activity	Protein Binding Protein Domain Specific Binding Identical Protein Binding MIT Domain Binding
	Biological Process	Actomyosin Contractile Ring Contraction Plasma Membrane Repair Protein Targeting To Lysosome Vesicle Budding From Membrane Autophagy Nucleus Organization Nuclear Envelope Organization Endosome Organization Vacuole Organization Lysosomal Transport Mitotic Metaphase Chromosome Alignment Mitotic Nuclear Membrane Reassembly Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Vesicle-mediated Transport Endosomal Transport Macroautophagy Viral Release From Host Cell Nuclear Membrane Reassembly Intracellular Cholesterol Transport Negative Regulation Of Cytokinesis Regulation Of Protein Localization Endosomal Vesicle Fusion Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Protein Depolymerization Cell Division Cytoskeleton-dependent Cytokinesis Late Endosomal Microautophagy Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Midbody Abscission Multivesicular Body Sorting Pathway Vesicle Uncoating Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Exosomal Secretion Positive Regulation Of Viral Budding Via Host ESCRT Complex ESCRT Complex Disassembly ESCRT III Complex Disassembly	Plasma Membrane Repair Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Protein Transport Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Cell Division Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol ( 30275531) Logical memory (delayed recall) in normal cognition ( 29274321) Total cholesterol levels in HDL ( 29084231)	Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: CFTR CHMP1A CHMP1B CHMP2A CHMP4A CHMP4B CHMP4C CLIC3 NPC1 OGT RND2 SNCA VPS4B	19 interacting genes: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN MITD1 PICK1 RAB11A RASSF7 SNCA SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B
Entrez ID		27183	57132
HPRD ID		11676	12106
Ensembl ID		ENSG00000132612	ENSG00000255112
Uniprot IDs		Q9UN37	Q7LBR1
PDB IDs		1YXR 2JQ9 2K3W	3EAB 3JC1 4TXQ 4TXR 6E8G 6TZ4 6TZ5 6TZ9 8V2Q 8V2R 8V2S
Enriched GO Terms of Interacting Partners?		Viral Budding From Plasma Membrane Late Endosome To Lysosome Transport Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body-lysosome Fusion Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Lysosomal Membrane Organization Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Kinetochore Microtubule Nuclear Membrane Organization Autophagosome Maturation Metaphase Chromosome Alignment Membrane Assembly Lysosomal Transport Multivesicular Body Membrane Chromosome Localization Biological Process Involved In Interaction With Host Endosome Organization Regulation Of Microtubule Cytoskeleton Organization Nuclear Pore Vacuolar Transport Autophagy Nucleus Organization Multivesicular Body Regulation Of Centrosome Duplication Autophagosome Membrane Plasma Membrane Organization Regulation Of Centrosome Cycle Regulation Of Microtubule-based Process Protein-containing Complex Disassembly Viral Process Organelle Localization	Cytokinetic Process Viral Budding Via Host ESCRT Complex Midbody Abscission Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process Multivesicular Body Assembly Multivesicular Body Organization Viral Budding From Plasma Membrane Endosome Organization Cytoskeleton-dependent Cytokinesis Membrane Fission Mitotic Metaphase Chromosome Alignment Late Endosome To Lysosome Transport Midbody Nuclear Membrane Organization Multivesicular Body Sorting Pathway Metaphase Chromosome Alignment Membrane Assembly Mitotic Cytokinesis Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromosome Localization ESCRT III Complex Disassembly ESCRT Complex Disassembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Endosome Autophagosome Maturation Kinetochore Microtubule Protein-containing Complex Disassembly Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Vesicle Organization Nuclear Pore Nucleus Organization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Multivesicular Body ESCRT III Complex Plasma Membrane Organization Amphisome Membrane Vesicle Fusion With Vacuole Lysosomal Transport Regulation Of Centrosome Duplication
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