VPS4A and CHMP1B

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		VPS4A	CHMP1B
Gene Name		vacuolar protein sorting 4 homolog A (S. cerevisiae)	charged multivesicular body protein 1B
Image
Gene Ontology Annotations	Cellular Component	ESCRT III Complex Spindle Pole Nucleus Cytoplasm Centrosome Cytosol Midbody Late Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Flemming Body	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity Protein Domain Specific Binding ATPase Activity, Coupled	Protein Binding Protein Domain Specific Binding
	Biological Process	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuole Organization Mitotic Metaphase Plate Congression Abscission Protein Transport Viral Process Vesicle-mediated Transport Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Negative Regulation Of Cytokinesis Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Establishment Of Protein Localization Regulation Of Mitotic Spindle Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CHMP1A CHMP1B CHMP2A CHMP4A CHMP4B CHMP4C NPC1 RND2 VPS4B	16 interactors: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B
Entrez ID		27183	57132
HPRD ID		11676	12106
Ensembl ID		ENSG00000132612	ENSG00000255112
Uniprot IDs		Q9UN37	Q7LBR1
PDB IDs		1YXR 2JQ9 2K3W	3EAB
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Regulation Of Mitotic Spindle Assembly Mitotic Metaphase Plate Congression Regulation Of Spindle Assembly Metaphase Plate Congression Regulation Of Mitotic Spindle Organization Establishment Of Chromosome Localization Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Regulation Of Centrosome Duplication Nucleus Organization Regulation Of Centrosome Cycle Viral Budding Via Host ESCRT Complex Chromosome Segregation Positive Regulation Of Viral Release From Host Cell Viral Budding Regulation Of Mitotic Nuclear Division Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Organelle Localization Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Regulation Of Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cell Cycle Process Regulation Of Protein Complex Assembly Mitotic Cell Cycle Establishment Of Protein Localization Regulation Of Mitotic Cell Cycle Intracellular Transport Viral Life Cycle Regulation Of Organelle Organization Regulation Of Cell Cycle Process Endosomal Transport Regulation Of Cytoskeleton Organization Chromosome Organization Positive Regulation Of Viral Process Cell Cycle Process Negative Regulation Of Macroautophagy Membrane Budding Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Cell Cycle Protein Transport Cellular Localization	Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Cell Division Mitotic Sister Chromatid Segregation Metaphase Plate Congression Sister Chromatid Segregation Establishment Of Chromosome Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cytokinesis Chromosome Segregation Regulation Of Mitotic Spindle Organization Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Nuclear Division Regulation Of Microtubule-based Process Cell Cycle Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Nucleus Organization Regulation Of Centrosome Duplication Viral Budding Regulation Of Centrosome Cycle Establishment Of Organelle Localization Chromosome Organization Organelle Localization Endosomal Transport Virion Assembly Regulation Of Cell Cycle Process Regulation Of Cell Division Regulation Of Cytoskeleton Organization Endosome Organization Regulation Of Mitotic Nuclear Division Mitotic Cytokinesis Regulation Of Mitotic Cell Cycle Organelle Organization Viral Life Cycle Positive Regulation Of Viral Release From Host Cell Cellular Macromolecule Catabolic Process Positive Regulation Of Viral Process Regulation Of Organelle Organization Vacuolar Transport Regulation Of Cell Cycle Membrane Budding Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion
Tagcloud ?		aip1 budding detail dn e3 escrt gag htlv infant invagination mother motif multivesicular mvb nedd4 polyprotein pppy ptap sorting tsg101 utilizes vertical vesicles vlps vps28 vps37 vps4b ww	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Difference) ?		aip1 budding detail dn e3 gag htlv infant invagination mother motif nedd4 polyprotein pppy ptap sorting tsg101 utilizes vertical vesicles vlps vps28 vps37 vps4b ww	aux1 auxin disorganized endosomal gradients internalized lip5 lumenal meristems mislocalized mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Intersection) ?		escrt multivesicular mvb