VPS4A and RND2

Number of citations of the paper that reports this interaction (PMID 11931639)
4

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		VPS4A	RND2
Gene Name		vacuolar protein sorting 4 homolog A (S. cerevisiae)	Rho family GTPase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT III Complex Spindle Pole Nucleus Cytoplasm Centrosome Cytosol Midbody Late Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Flemming Body	Acrosomal Membrane Early Endosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity Protein Domain Specific Binding ATPase Activity, Coupled	GTPase Activity Protein Binding GTP Binding Protein N-terminus Binding
	Biological Process	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuole Organization Mitotic Metaphase Plate Congression Abscission Protein Transport Viral Process Vesicle-mediated Transport Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Negative Regulation Of Cytokinesis Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Collateral Sprouting
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CHMP1A CHMP1B CHMP2A CHMP4A CHMP4B CHMP4C NPC1 RND2 VPS4B	6 interactors: ARHGAP5 FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A
Entrez ID		27183	8153
HPRD ID		11676	03332
Ensembl ID		ENSG00000132612	ENSG00000108830
Uniprot IDs		Q9UN37	P52198
PDB IDs		1YXR 2JQ9 2K3W
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Regulation Of Mitotic Spindle Assembly Mitotic Metaphase Plate Congression Regulation Of Spindle Assembly Metaphase Plate Congression Regulation Of Mitotic Spindle Organization Establishment Of Chromosome Localization Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Regulation Of Centrosome Duplication Nucleus Organization Regulation Of Centrosome Cycle Viral Budding Via Host ESCRT Complex Chromosome Segregation Positive Regulation Of Viral Release From Host Cell Viral Budding Regulation Of Mitotic Nuclear Division Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Organelle Localization Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Regulation Of Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cell Cycle Process Regulation Of Protein Complex Assembly Mitotic Cell Cycle Establishment Of Protein Localization Regulation Of Mitotic Cell Cycle Intracellular Transport Viral Life Cycle Regulation Of Organelle Organization Regulation Of Cell Cycle Process Endosomal Transport Regulation Of Cytoskeleton Organization Chromosome Organization Positive Regulation Of Viral Process Cell Cycle Process Negative Regulation Of Macroautophagy Membrane Budding Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Cell Cycle Protein Transport Cellular Localization	Cell Separation After Cytokinesis Regulation Of Cytokinesis Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Abscission Somite Specification Mitotic Spindle Midzone Assembly Viral Budding Via Host ESCRT Complex Regulation Of Cell Division Mitotic Spindle Elongation Mitotic Cytokinetic Process Viral Budding Negative Regulation Of Cytokinesis Spindle Midzone Assembly Mitotic Nuclear Division Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Segment Specification Cell Division Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Virion Assembly Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Metaphase Plate Congression
Tagcloud ?		aip1 budding detail dn e3 escrt gag htlv infant invagination mother motif multivesicular mvb nedd4 polyprotein pppy ptap sorting tsg101 utilizes vertical vesicles vlps vps28 vps37 vps4b ww	actin actomyosin antagonise atypical bypass contractility cytoskeleton explain extension gtp gtpase hydrolyse inhibiting limit neurite propose reducing regulating regulators relatives rho rhoa rhoe rnd1 rnd3 rock separate smooth thereby
Tagcloud (Difference) ?		aip1 budding detail dn e3 escrt gag htlv infant invagination mother motif multivesicular mvb nedd4 polyprotein pppy ptap sorting tsg101 utilizes vertical vesicles vlps vps28 vps37 vps4b ww	actin actomyosin antagonise atypical bypass contractility cytoskeleton explain extension gtp gtpase hydrolyse inhibiting limit neurite propose reducing regulating regulators relatives rho rhoa rhoe rnd1 rnd3 rock separate smooth thereby
Tagcloud (Intersection) ?