SLC39A1 and KCNAB2

Number of citations of the paper that reports this interaction (PMID 10477520)
19

Data Source:
HPRD (two hybrid)

		SLC39A1	KCNAB2
Gene Name		solute carrier family 39 (zinc transporter), member 1	potassium channel, voltage gated subfamily A regulatory beta subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Juxtaparanode Region Of Axon Pinceau Fiber
	Molecular Function	Receptor Binding Zinc Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Cation Transport Transmembrane Transport Zinc Ion Transmembrane Transport	Hematopoietic Progenitor Cell Differentiation Synaptic Transmission Protein Heterooligomerization Oxidation-reduction Process NADPH Oxidation Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface
Pathways		Metal ion SLC transporters Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc influx into cells by the SLC39 gene family Zinc transporters SLC-mediated transmembrane transport	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Lentiform nucleus volume ( 22903471)
Protein-Protein Interactions		8 interactors: CERS2 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2	8 interactors: ATXN1 CD4 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1
Entrez ID		27173	8514
HPRD ID		11984	03090
Ensembl ID		ENSG00000143570	ENSG00000069424
Uniprot IDs		B4DDY7 Q9NY26	B2R776 Q13303 Q2YD85
PDB IDs			1ZSX
Enriched GO Terms of Interacting Partners?		Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Synaptic Transmission Protein Heterooligomerization Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production NADPH Oxidation Activation Of Phospholipase D Activity Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Cell-cell Signaling Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of T Cell Cytokine Production Cation Transmembrane Transport Positive Regulation Of T-helper 2 Cell Differentiation Glomerular Capillary Formation Learning Or Memory Regulation Of Interleukin-10 Secretion Cognition Positive Regulation Of Interleukin-4 Production Positive Regulation Of Insulin Receptor Signaling Pathway Angiogenesis Regulation Of T Cell Cytokine Production Cation Transport Regulation Of Interleukin-5 Production Glomerulus Morphogenesis Positive Regulation Of Type 2 Immune Response	Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Zinc Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Zinc Ion Transport Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Metal Ion Transport Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Ion Transmembrane Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Induction By Virus Of Host Cell-cell Fusion Transmission Of Virus Protein Palmitoleylation Development Involved In Symbiotic Interaction Action Potential Cation Transport Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Interaction With Host Ion Transmembrane Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Optic Nerve Structural Organization Positive Regulation Of Caveolin-mediated Endocytosis Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Signal Transduction Regulation Of Ion Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Protein Polyubiquitination Regulation Of Signaling Transmembrane Transport Regulation Of Cellular Response To Growth Factor Stimulus Ion Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Caveolin-mediated Endocytosis Progesterone Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Sodium Ion Transmembrane Transport
Tagcloud ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic
Tagcloud (Difference) ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic
Tagcloud (Intersection) ?