SLC39A1 and SLC39A2

Number of citations of the paper that reports this interaction (PMID 10477520)
19

Data Source:
HPRD (two hybrid)

		SLC39A1	SLC39A2
Gene Name		solute carrier family 39 (zinc transporter), member 1	solute carrier family 39 (zinc transporter), member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Receptor Binding Zinc Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity	Zinc Ion Transmembrane Transporter Activity
	Biological Process	Cation Transport Transmembrane Transport Zinc Ion Transmembrane Transport	Zinc Ion Transport Transmembrane Transport Zinc Ion Transmembrane Transport
Pathways		Metal ion SLC transporters Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc influx into cells by the SLC39 gene family Zinc transporters SLC-mediated transmembrane transport	Metal ion SLC transporters Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc influx into cells by the SLC39 gene family Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Lentiform nucleus volume ( 22903471)
Protein-Protein Interactions		8 interactors: CERS2 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2	3 interactors: KCNAB1 KCNAB2 SLC39A1
Entrez ID		27173	29986
HPRD ID		11984	15385
Ensembl ID		ENSG00000143570	ENSG00000165794
Uniprot IDs		B4DDY7 Q9NY26	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Synaptic Transmission Protein Heterooligomerization Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production NADPH Oxidation Activation Of Phospholipase D Activity Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Cell-cell Signaling Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of T Cell Cytokine Production Cation Transmembrane Transport Positive Regulation Of T-helper 2 Cell Differentiation Glomerular Capillary Formation Learning Or Memory Regulation Of Interleukin-10 Secretion Cognition Positive Regulation Of Interleukin-4 Production Positive Regulation Of Insulin Receptor Signaling Pathway Angiogenesis Regulation Of T Cell Cytokine Production Cation Transport Regulation Of Interleukin-5 Production Glomerulus Morphogenesis Positive Regulation Of Type 2 Immune Response	Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Metal Ion Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Potassium Ion Transmembrane Transport Potassium Ion Transport Transmembrane Transport Ion Transport NADPH Oxidation Regulation Of Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Protein Localization To Cell Surface Zinc Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Zinc Ion Transport Cell-cell Signaling NADP Metabolic Process Transport Regulation Of Cation Channel Activity Nicotinamide Nucleotide Metabolic Process Oxidation-reduction Process Protein Heterooligomerization Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Hematopoietic Progenitor Cell Differentiation
Tagcloud ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic
Tagcloud (Difference) ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic
Tagcloud (Intersection) ?