SLC39A1 and KCNAB1

Number of citations of the paper that reports this interaction (PMID 10477520)
19

Data Source:
HPRD (two hybrid)

		SLC39A1	KCNAB1
Gene Name		solute carrier family 39 (zinc transporter), member 1	potassium channel, voltage gated subfamily A regulatory beta subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Potassium Channel Complex
	Molecular Function	Receptor Binding Zinc Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity NADPH Binding
	Biological Process	Cation Transport Transmembrane Transport Zinc Ion Transmembrane Transport	Potassium Ion Transport Synaptic Transmission Learning Or Memory Oxidation-reduction Process Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Metal ion SLC transporters Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc influx into cells by the SLC39 gene family Zinc transporters SLC-mediated transmembrane transport	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS		Lentiform nucleus volume ( 22903471)	Aging traits ( 17903295)
Protein-Protein Interactions		8 interactors: CERS2 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2	8 interactors: APP DLG1 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1
Entrez ID		27173	7881
HPRD ID		11984	03089
Ensembl ID		ENSG00000143570	ENSG00000169282
Uniprot IDs		B4DDY7 Q9NY26	B7Z435 B7Z8E5 F8W6W4 Q14722
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Synaptic Transmission Protein Heterooligomerization Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production NADPH Oxidation Activation Of Phospholipase D Activity Potassium Ion Transmembrane Transport Potassium Ion Transport Metal Ion Transport Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Cell-cell Signaling Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of T Cell Cytokine Production Cation Transmembrane Transport Positive Regulation Of T-helper 2 Cell Differentiation Glomerular Capillary Formation Learning Or Memory Regulation Of Interleukin-10 Secretion Cognition Positive Regulation Of Interleukin-4 Production Positive Regulation Of Insulin Receptor Signaling Pathway Angiogenesis Regulation Of T Cell Cytokine Production Cation Transport Regulation Of Interleukin-5 Production Glomerulus Morphogenesis Positive Regulation Of Type 2 Immune Response	Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Regulation Of Ion Transmembrane Transport Viral Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Zinc Ion Transmembrane Transport Regulation Of Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Zinc Ion Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Metal Ion Transport Neuromuscular Junction Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Action Potential Cation Transport Regulation Of Synapse Structure Or Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transport Immune Response Ion Transmembrane Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Optic Nerve Structural Organization Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Cell Recognition Regulation Of Ion Transmembrane Transporter Activity Collateral Sprouting In Absence Of Injury Regulation Of Transmembrane Transporter Activity Cell Activation Protein Polyubiquitination Synapse Organization Positive Regulation Of Transport Transport T Cell Cytokine Production Collateral Sprouting Axon Midline Choice Point Recognition Transmembrane Transport Regulation Of Cellular Response To Growth Factor Stimulus Ion Transport Cell Development Positive Regulation Of Ion Transport Progesterone Receptor Signaling Pathway
Tagcloud ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic	430v2 affymetrix alpha1 anatomical antipsychotic clozapine coregulation developmentally dysregulation encode gated haloperidol inbred kchip3 kv kv1 kvbeta1 nedd4 neurogenesis neurotransmission olanzapine psychotic rodent shaker subfamily thirteen undertaken voltage
Tagcloud (Difference) ?		aco1 annotations atp7b caco conditioned dcytb duodenal enterocyte fech fth1 hemochromatosis heph hfe1 highlight invariant iron metabolism microarrays modulated nucleocytoplasmic ontological place regard slc11a2 slc11a3 taking tf transcriptomic xenobiotic	430v2 affymetrix alpha1 anatomical antipsychotic clozapine coregulation developmentally dysregulation encode gated haloperidol inbred kchip3 kv kv1 kvbeta1 nedd4 neurogenesis neurotransmission olanzapine psychotic rodent shaker subfamily thirteen undertaken voltage
Tagcloud (Intersection) ?