TJP3 and CLDN1

Number of citations of the paper that reports this interaction (PMID 10601346)
178

Data Source:
HPRD (in vivo, in vitro)

		TJP3	CLDN1
Gene Name		tight junction protein 3	claudin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Tight Junction Apical Plasma Membrane Cell Junction	Integral Component Of Plasma Membrane Tight Junction Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cell Adhesion Viral Process Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Establishment Of Skin Barrier
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Working memory ( 21107309)
Protein-Protein Interactions		5 interactors: CLDN1 FASLG GJC1 INADL TJP1	12 interactors: BRD4 CLDN3 DRG1 INADL LNX1 MMP14 MMP2 MPDZ TJP1 TJP2 TJP3 WNK4
Entrez ID		27134	9076
HPRD ID		18194	04760
Ensembl ID		ENSG00000105289	ENSG00000163347
Uniprot IDs		B3KR73 F5H2X0 O95049	A5JSJ9 O95832
PDB IDs		3KFV
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Organization Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Glucose Chemical Homeostasis Cell-cell Signaling Endosomal Lumen Acidification Response To Carbohydrate Response To Magnetism Retinal Cell Programmed Cell Death Necroptotic Signaling Pathway Establishment Of Endothelial Intestinal Barrier Response To Lipopolysaccharide Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Homeostatic Process Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Chloride Ion Homeostasis Response To Molecule Of Bacterial Origin Positive Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Vascular Permeability Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Skin Barrier T Cell Apoptotic Process Cell Development Response To Bacterium Regulation Of Water Loss Via Skin Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cellular Component Assembly PH Reduction Cellular Chemical Homeostasis Gap Junction Assembly Positive Regulation Of ERBB Signaling Pathway Establishment Of Endothelial Barrier Cardiac Muscle Cell Action Potential Involved In Contraction Hippo Signaling Endosome Organization Necroptotic Process Regulation Of Vascular Permeability Multicellular Organismal Development Regulation Of Endothelial Cell Apoptotic Process Anatomical Structure Development Cardiac Muscle Cell Action Potential Cellular Homeostasis Blastocyst Formation Developmental Programmed Cell Death	Establishment Of Endothelial Intestinal Barrier Response To Hypoxia Anatomical Structure Development Establishment Of Endothelial Barrier Hippo Signaling Tissue Development Epithelium Development Response To Abiotic Stimulus Epithelial Cell Development Endodermal Cell Differentiation Regulation Of Cell Cycle Checkpoint Developmental Process Endothelial Cell Development Endoderm Formation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Collagen Catabolic Process Cell-cell Signaling Involved In Cell-cell Junction Organization Execution Phase Of Apoptosis Collagen Metabolic Process Endothelial Cell Differentiation Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Multicellular Organismal Metabolic Process Endothelium Development Extracellular Matrix Disassembly Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Blastocyst Development Cell Development Intracellular Signal Transduction Distal Tubule Morphogenesis Cell-cell Junction Assembly Regulation Of Cell Cycle Process Embryo Development Formation Of Primary Germ Layer Negative Regulation Of DNA Damage Checkpoint Renal Sodium Ion Absorption Response To Magnetism Histone H3-K14 Acetylation Epithelial Cell Differentiation Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Myelination Axon Ensheathment Positive Regulation Of Spindle Checkpoint Cell Differentiation Multicellular Organismal Development Astrocyte Cell Migration Gastrulation Histone H4-K12 Acetylation Intramembranous Ossification
Tagcloud ?		adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing	aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing	aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?