TJP3 and GJC1

Number of citations of the paper that reports this interaction (PubMedID 11557048)
0

Data Source:
HPRD (two hybrid)

		TJP3	GJC1
Description		tight junction protein 3	gap junction protein gamma 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction Tight Junction Anchoring Junction	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Connexin Complex Intercalated Disc Membrane Synapse Anchoring Junction
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding	Monoatomic Ion Channel Activity Gap Junction Channel Activity Protein Binding Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
	Biological Process	Maintenance Of Blood-brain Barrier Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability	Vasculogenesis Muscle Contraction Cell-cell Junction Assembly Cell Communication Cell-cell Signaling Chemical Synaptic Transmission Heart Development Visual Perception Gap Junction Assembly Monoatomic Ion Transmembrane Transport Cell Development Cardiac Muscle Tissue Development Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Pathways			Electric Transmission Across Gap Junctions Gap junction assembly
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
Interacting Genes		5 interacting genes: CLDN1 FASLG GJC1 PATJ TJP1	8 interacting genes: APOL3 CNST MEOX2 SLC66A1 TJP1 TJP3 TMEM86A UBQLN4
Entrez ID		27134	10052
HPRD ID		18194	08819
Ensembl ID		ENSG00000105289	ENSG00000182963
Uniprot IDs		O95049	P36383
PDB IDs		3KFV	3SHW
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Assembly Cell-cell Junction Organization Tight Junction Cell Junction Assembly Anchoring Junction Cell Junction Organization Bicellular Tight Junction Establishment Of Endothelial Intestinal Barrier Regulation Of Bicellular Tight Junction Assembly Cell Junction Gap Junction Apical Junction Complex Maintenance Of Blood-brain Barrier Establishment Of Endothelial Barrier Endothelial Cell Development Cell Junction Maintenance Tight Junction Assembly Tight Junction Organization Cellular Component Maintenance Cellular Response To Type II Interferon Apical Part Of Cell Xenobiotic Transport Across Blood-nerve Barrier Response To Type II Interferon Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Epithelial Cell Development Cellular Response To Butyrate SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Retinal Cell Programmed Cell Death Response To Butyrate Cellular Response To Lead Ion Response To Interleukin-18 Establishment Of Blood-nerve Barrier Cytoplasmic Vesicle Lumen Anatomical Structure Homeostasis Tissue Homeostasis AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Cell Development Plasma Membrane Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phospholipid Translocation Positive Regulation Of Blood-brain Barrier Permeability Protein Localization To Adherens Junction Inflammatory Cell Apoptotic Process Protein Localization To Bicellular Tight Junction Adherens Junction Maintenance Cellular Component Assembly Basolateral Plasma Membrane	Positive Regulation Of Blood-brain Barrier Permeability Regulation Of Blood-brain Barrier Permeability Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Vascular Permeability Protein Localization To Cell-cell Junction Maintenance Of Blood-brain Barrier Tight Junction Establishment Of Endothelial Barrier Endothelial Cell Development Regulation Of Vascular Permeability Protein Localization To Cell Junction Cell Adhesion Molecule Binding Lysine Transport Nuclear Proteasome Complex Alkenylglycerophosphocholine Hydrolase Activity Bicellular Tight Junction Negative Regulation Of Autophagosome Maturation Epithelial Cell Development Somite Specification Protein Localization To Bicellular Tight Junction Adherens Junction Maintenance Protein Localization To Adherens Junction L-lysine Transmembrane Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport Cytosolic Proteasome Complex Positive Regulation Of Golgi To Plasma Membrane Protein Transport Connexin Binding Cell-cell Junction Organization Anatomical Structure Homeostasis Tissue Homeostasis Ameloblast Differentiation Cell Junction Protein-containing Complex Basic Amino Acid Transmembrane Transporter Activity Intracellular Amino Acid Homeostasis L-arginine Transmembrane Transporter Activity Aromatic Amino Acid Transport K48-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin L-arginine Transmembrane Transport Regulation Of Golgi To Plasma Membrane Protein Transport Azole Transmembrane Transport Vascular Process In Circulatory System
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