GJA8 and TMEM128

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GJA8	TMEM128
Description		gap junction protein alpha 8	transmembrane protein 128
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Gap Junction Connexin Complex Membrane Anchoring Junction	Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Cell Communication Cell-cell Signaling Camera-type Eye Development Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		Retinopathy x type 2 diabetes interaction ( 32541925) Triglyceride levels ( 34074324)	Glomerular filtration rate ( 24351856)
Interacting Genes		125 interacting genes: ABL1 ACKR2 APOA2 APOD APOL3 AQP4 ARL6IP6 ATP6V0B C1GALT1 C2CD2L C3orf52 CCDC167 CCL4 CD53 CIAO2A CLDN19 CLDN4 CLEC1A CLN6 COX20 CTXN3 CXCL16 CYBC1 CYP4F2 DEFB121 DOLK ERMP1 FDFT1 FXYD6 GIMAP1 GIMAP5 GJB2 GPR108 GPR151 GPR61 GUCA2A IGFBP5 INSIG2 ITGAM KIR2DL3 LAPTM4B LAT LEPROTL1 LHFPL5 MAL MALL MARCHF2 MFSD11 MFSD6 MGST2 MIP MS4A13 NINJ2 ORMDL2 OTOP2 P2RY13 PGAP2 PLN PLP1 PMP22 PNLIPRP1 PRAF2 PROKR2 PTPRN QRFPR REEP6 RNF152 RUSF1 RXFP4 S1PR5 SCARF1 SEC22B SEC22C SEC23A SFTPC SLC13A2 SLC13A5 SLC16A12 SLC16A13 SLC16A3 SLC30A3 SLC35A4 SLC35F1 SLC35F6 SLC38A4 SLC38A7 SLC39A2 SLC39A7 SLC39A9 SLC52A1 SLC66A1 SLC66A2 SLC8A3 SMCO4 SMIM1 STX1B STX8 THSD7B TJP1 TMBIM6 TMEM100 TMEM107 TMEM121 TMEM128 TMEM147 TMEM182 TMEM239 TMEM242 TMEM243 TMEM42 TMEM45A TMEM60 TMEM65 TMEM72 TMEM86B TMEM97 TSPAN33 TWSG1 UBXN8 UNC93A UPK1B VAMP5 VAPB YIF1A YIPF6	66 interacting genes: AQP6 ARL13B BCL2L13 BEST2 CD40 CD53 CD79A CLDN5 CLDN7 CLN8 CPLX4 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM209A FFAR2 GAD2 GJA1 GJA8 GJB5 GORAB GPR152 GPR42 GPX8 HSD17B11 HSD17B13 IER3IP1 IL3RA JAGN1 KCNK5 LEUTX LHFPL2 LHFPL5 LMNA MAPK8IP2 MFF MRPS18B MTERF1 MTIF3 MUC1 REEP4 RETREG3 SCN3B SEC11C SHISAL1 SLC10A6 SLC18A1 SLC1A3 SLC26A6 SLC34A2 SLC35H1 SLC61A1 SLC7A14 SSMEM1 STX1A TMEM106A TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 ZDHHC15 ZFYVE27
Entrez ID		2703	85013
HPRD ID		02939	17483
Ensembl ID		ENSG00000121634	ENSG00000132406
Uniprot IDs		P48165 X5D7G1	B7Z3K1 Q5BJH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Transmembrane Transport Zinc Ion Transmembrane Transporter Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Zinc Ion Transmembrane Transport Structural Constituent Of Myelin Sheath Zinc Ion Transport Transmembrane Transporter Activity Fumarate Transport Carboxylic Acid Transport Organic Acid Transport Sodium:dicarboxylate Symporter Activity Chemical Homeostasis Organic Anion Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Homeostatic Process Cholesterol Binding Metal Ion Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Succinate Transport Succinate Transmembrane Transport COPII-coated Vesicle Budding	Membrane Protein Binding Endoplasmic Reticulum Organization Endoplasmic Reticulum Transmembrane Transport Inorganic Anion Transport Acidic Amino Acid Transport Neurotransmitter Transport Endoplasmic Reticulum Membrane Connexin Complex Steroid Dehydrogenase Activity Organic Anion Transport Gap Junction Channel Activity Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Plasma Membrane Gap Junction Monoatomic Ion Transport Dicarboxylic Acid Transport Neurotransmitter Uptake Gamma-aminobutyric Acid Biosynthetic Process Gamma-aminobutyric Acid Metabolic Process Carboxylic Acid Transport Organic Acid Transport Atrial Cardiac Muscle Cell Action Potential Chloride Transmembrane Transport Chloride Transport L-glutamate Import Across Plasma Membrane Efflux Transmembrane Transporter Activity
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