ZNF366 and AKAP8L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF366	AKAP8L
Description		zinc finger protein 366	A-kinase anchoring protein 8 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Nuclear Estrogen Receptor Binding Metal Ion Binding	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly
Pathways			Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Asthma (childhood onset) ( 31036433) Bone mineral density (Ward's triangle area) ( 27397699) Heel bone mineral density ( 30598549) Hip geometry ( 17903296) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)	Red blood cell count ( 32888494)
Interacting Genes		5 interacting genes: AKAP8L CARD10 CEP70 PSMA3 TRIM54	60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366
Entrez ID		167465	26993
HPRD ID		18329	10641
Ensembl ID		ENSG00000178175	ENSG00000011243
Uniprot IDs		Q8N895	Q9ULX6
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein Binding Sperm Flagellum
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