GDI1 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10751420)
0

Data Source:
HPRD (in vitro, in vivo)

		GDI1	RABAC1
Description		GDP dissociation inhibitor 1	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath Presynaptic Cytosol	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Signal Transduction Small GTPase-mediated Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane Negative Regulation Of Protein Localization
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS			Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		19 interacting genes: CDC42 EPB41 GNL1 LINC00632 LNX1 OGT PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH RUNX1 TK1 UBQLN4 USP25	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		2664	10567
HPRD ID		02114	05375
Ensembl ID		ENSG00000203879	ENSG00000105404
Uniprot IDs		A0A0S2Z3X8 P31150	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Myosin V Binding Nucleotide Binding G Protein Activity Regulation Of Vesicle-mediated Transport Hydrolase Activity Regulation Of Proteolysis Intracellular Protein Localization Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Golgi Apparatus Regulation Of Exocytosis GDP Binding Regulation Of Synaptic Vesicle Cycle Immune System Process Endoplasmic Reticulum Membrane Protein-containing Complex Antigen Processing And Presentation Small GTPase-mediated Signal Transduction GTP-dependent Protein Binding Autophagy Cytoplasmic Vesicle Positive Regulation Of Lamellipodium Assembly Protein Localization To Golgi Apparatus Synaptic Vesicle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Myeloid Leukocyte Differentiation Positive Regulation Of Lamellipodium Organization Golgi Membrane Leukocyte Differentiation Regulation Of Lamellipodium Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Core Promoter Binding Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Peptidyl-cysteine Methylation Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Neuron Projection Organization Cortical Cytoskeleton Organization Protein Transport Regulation Of Lamellipodium Organization	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?