ITGB1BP2 and PPHLN1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		ITGB1BP2	PPHLN1
Description		integrin subunit beta 1 binding protein 2	periphilin 1
Image		No pdb structure
GO Annotations	Cellular Component	Z Disc	Nucleus Nucleoplasm Chromosome Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	Integrin Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Signal Transduction Muscle Organ Development Centrosome Duplication	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Protein Localization To Heterochromatin Constitutive Heterochromatin Formation
Pathways			Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: HSP90AA1 HSP90AB1 ITGB1 PPHLN1 PUM3 RARA RARG SGCA SH3GLB1 STAG2 TKT TTN UGDH WASL	27 interacting genes: APP BCL2L1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 FXR1 ITGB1BP2 MTUS2 NAGK OGT PAXIP1 PPL SEPTIN8 SHANK3 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM
Entrez ID		26548	51535
HPRD ID		02271	10488
Ensembl ID		ENSG00000147166	ENSG00000134283
Uniprot IDs		Q9UKP3	F8W6A0 Q8NEY8
PDB IDs			6SWG
Enriched GO Terms of Interacting Partners?		Trachea Cartilage Development Glandular Epithelial Cell Development Telomerase Holoenzyme Complex Assembly Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Growth Plate Cartilage Development Regulation Of Protein Localization Melanosome Protein Kinase Regulator Activity Columnar/cuboidal Epithelial Cell Development Embryonic Camera-type Eye Development Regulation Of Plasma Membrane Organization Chaperone-mediated Protein Complex Assembly Chromosome Organization Telomere Maintenance Via Telomerase Histone Deacetylase Binding DNA Polymerase Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Retinoic Acid Receptor Signaling Pathway Face Development Protein Homodimerization Activity Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Protein-containing Complex Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex Negative Regulation Of Cartilage Development Skeletal Muscle Contraction Positive Regulation Of Protein Localization ATP-dependent Protein Folding Chaperone Cardiac Muscle Cell Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Protein Folding Muscle Contraction Positive Regulation Of Nitric Oxide Metabolic Process Extracellular Exosome Protein Tyrosine Kinase Binding Tau Protein Binding Supramolecular Fiber Organization Sarcomere Organization Regulation Of Myelination Anatomical Structure Morphogenesis CTP Binding DATP Binding Cellular Response To Heat Myoblast Fate Specification Cardiocyte Differentiation	Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cytoplasm Regulation Of Cell Cycle Regulation Of Neuron Apoptotic Process Intracellular Membraneless Organelle Cell Death Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Neuron Projection Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Long-term Synaptic Potentiation Cytosol Glial Cell Development Scaffold Protein Binding Autophagy Of Mitochondrion Regulation Of Defense Response Intracellular Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Programmed Cell Death Cytoskeleton Protein Targeting Apoptotic Process Cellular Response To Catecholamine Stimulus Astrocyte Development Presynapse Programmed Cell Death Response To Catecholamine Synapse Response To Muramyl Dipeptide Regulation Of Innate Immune Response Positive Regulation Of Mitophagy SH3 Domain Binding Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Modulation Of Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Synaptic Transmission Protein Binding Developmental Process Regulation Of Mitotic Cell Cycle Organelle Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?