ITGB1BP2 and SGCA

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		ITGB1BP2	SGCA
Description		integrin subunit beta 1 binding protein 2	sarcoglycan alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Z Disc	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Cell-cell Junction Dystrophin-associated Glycoprotein Complex Dystroglycan Complex Sarcoglycan Complex Membrane Sarcolemma Membrane Raft
	Molecular Function	Integrin Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Signal Transduction Muscle Organ Development Centrosome Duplication	Muscle Contraction Muscle Organ Development
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases			Limb-girdle muscular dystrophy (LGMD) Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F
GWAS			Heel bone mineral density ( 30598549) Keratoconus ( 33649486) Temporomandibular joint disorder ( 28081371) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		14 interacting genes: HSP90AA1 HSP90AB1 ITGB1 PPHLN1 PUM3 RARA RARG SGCA SH3GLB1 STAG2 TKT TTN UGDH WASL	8 interacting genes: FN1 FSTL1 ITGB1BP2 SGCB SGCD SGTA SGTB TAF1
Entrez ID		26548	6442
HPRD ID		02271	02525
Ensembl ID		ENSG00000147166	ENSG00000108823
Uniprot IDs		Q9UKP3	A0A0S2Z4P8 A0A0S2Z4Q1 Q16586
PDB IDs
Enriched GO Terms of Interacting Partners?		Trachea Cartilage Development Glandular Epithelial Cell Development Telomerase Holoenzyme Complex Assembly Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Growth Plate Cartilage Development Regulation Of Protein Localization Melanosome Protein Kinase Regulator Activity Columnar/cuboidal Epithelial Cell Development Embryonic Camera-type Eye Development Regulation Of Plasma Membrane Organization Chaperone-mediated Protein Complex Assembly Chromosome Organization Telomere Maintenance Via Telomerase Histone Deacetylase Binding DNA Polymerase Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Retinoic Acid Receptor Signaling Pathway Face Development Protein Homodimerization Activity Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Protein-containing Complex Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex Negative Regulation Of Cartilage Development Skeletal Muscle Contraction Positive Regulation Of Protein Localization ATP-dependent Protein Folding Chaperone Cardiac Muscle Cell Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Protein Folding Muscle Contraction Positive Regulation Of Nitric Oxide Metabolic Process Extracellular Exosome Protein Tyrosine Kinase Binding Tau Protein Binding Supramolecular Fiber Organization Sarcomere Organization Regulation Of Myelination Anatomical Structure Morphogenesis CTP Binding DATP Binding Cellular Response To Heat Myoblast Fate Specification Cardiocyte Differentiation	TRC Complex Sarcoglycan Complex Dystroglycan Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Muscle Organ Development Dystrophin-associated Glycoprotein Complex Muscle Structure Development Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cardiac Muscle Cell Development Cardiac Cell Development Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Androgen Receptor Signaling Pathway Protein Targeting To Membrane Striated Muscle Cell Development Response To Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Endothelial Cell Migration Negative Regulation Of Protein Autoubiquitination Microtubule Nucleator Activity Muscle Cell Development Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Identical Protein Binding Sarcolemma Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Calcium-independent Cell-matrix Adhesion BAT3 Complex Binding Acetyl-CoA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process RNA Polymerase I General Transcription Initiation Factor Activity Histone H4K16ac Reader Activity Polar Microtubule Negative Regulation Of Proteolysis
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