HSPB8 and DUSP12

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HSPB8	DUSP12
Gene Name		heat shock 22kDa protein 8	dual specificity phosphatase 12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Cytoplasm Golgi Apparatus	Nucleus Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Binding Identical Protein Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Kinase Binding
	Biological Process	Biological_process	Cellular Protein Modification Process Protein Dephosphorylation Positive Regulation Of Glucokinase Activity Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BAG3 CRYAB CSNK2A1 DUSP12 HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 PRKCA QRICH1 SNCA	12 interactors: APP CALCOCO2 CCNH EIF5 HSPB8 KIAA1377 MBD6 NR1H2 PPP2R3B PTN RABAC1 USO1
Entrez ID		26353	11266
HPRD ID		06420	05323
Ensembl ID		ENSG00000152137	ENSG00000081721
Uniprot IDs		Q9UJY1	Q9UNI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Unfolded Protein Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Regulation Of Catalytic Activity Cell Death Death Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Response To Organic Substance Response To Interleukin-1 Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Response To Stress Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Platelet Activation Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Chromosome Organization Cellular Response To Growth Factor Stimulus Response To External Stimulus Negative Regulation Of Nucleotide Metabolic Process Response To Growth Factor Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Histone Acetylation Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Protein Metabolic Process Negative Regulation Of Endopeptidase Activity Cell Activation Negative Regulation Of Peptidase Activity Regulation Of Phosphorylation Positive Regulation Of Endothelial Cell Migration Protein Folding Regulation Of Protein Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Apolipoprotein Binding Positive Regulation Of Dense Core Granule Biogenesis	Mitotic Cell Cycle Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Synaptic Growth At Neuromuscular Junction Golgi Vesicle Docking Collateral Sprouting In Absence Of Injury Regulation Of High-density Lipoprotein Particle Assembly Learning Regulation Of Catalytic Activity Cell Cycle Negative Regulation Of Pinocytosis G1/S Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Axon Choice Point Recognition Intracellular Receptor Signaling Pathway Negative Regulation Of Cholesterol Storage Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Vesicle Fusion With Golgi Apparatus Positive Regulation Of Digestive System Process DNA-templated Transcription, Initiation Neuron Remodeling
Tagcloud ?		accordingly ala antiestrogens antiprogestins cdk2 cdks coactivators copurified cos deregulation disrupted g2 insensitive keys lysates pr probed progesterone progestin prs roscovitine s345a ser345 sp1 synchronized t47d talk transcriptionally transiently	bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Difference) ?		accordingly ala antiestrogens antiprogestins cdk2 cdks coactivators copurified cos deregulation disrupted g2 insensitive keys lysates pr probed progesterone progestin prs roscovitine s345a ser345 sp1 synchronized t47d talk transcriptionally transiently	bmp cacna1d ccl2 cd25 cd26 cdkn1a cml cure dpp4 dysregulation eradication exploited il1rap il2ra kcnk5 lscs marcks microarrays mycn oncogenes perp persistence ptprd refined slc4a4 timeless tki transcriptome withdrawal
Tagcloud (Intersection) ?