FAM50B and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM50B	CCDC57
Description		family with sequence similarity 50 member B	coiled-coil domain containing 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Intercellular Bridge	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromatin Organization	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)	Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		26240	284001
HPRD ID		16883	14150
Ensembl ID		ENSG00000145945	ENSG00000176155
Uniprot IDs		Q9Y247	A0A590UJT6 Q2TAC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Cytoskeleton Organelle Organization Cytoplasm Intracellular Protein Localization Protein Binding Protein Localization To Organelle Identical Protein Binding Nuclear Import Signal Receptor Activity Protein Transport Cellular Localization Intracellular Transport Spindle Organization Microtubule Organizing Center Organization Nuclear Pore Regulation Of Microtubule-based Process Centrosome Establishment Of Protein Localization Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Establishment Of Localization In Cell Telomere Localization Organelle Localization NLS-dependent Protein Nuclear Import Complex Protein Localization To Cytoskeleton Microtubule Microtubule Cytoskeleton Organization Involved In Mitosis Ubiquitin Protein Ligase Activity Spindle Midzone Assembly Cellular Component Assembly Protein Localization To Microtubule Microtubule Binding Positive Regulation Of Synaptic Transmission, GABAergic Enzyme Binding Negative Regulation Of Viral Transcription Membraneless Organelle Assembly Intermediate Filament Organization Regulation Of Microtubule Cytoskeleton Organization Transcription Coactivator Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Endocytic Recycling Regulation Of Viral Transcription Chromosome Localization Dynein Complex Binding Response To Muramyl Dipeptide	Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
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