IL13RA1 and TMEM39B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		IL13RA1	TMEM39B
Description		interleukin 13 receptor subunit alpha 1	transmembrane protein 39B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Interleukin-13 Receptor Complex External Side Of Plasma Membrane Membrane Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding	Protein Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway	Biological_process
Pathways		Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Body mass index ( 28892062) Type 2 diabetes ( 30718926)	Body mass index ( 26426971) Sleep duration (> 10 hours) ( 33075057)
Interacting Genes		7 interacting genes: DLG4 IL13 IL4R TMEM132D TMEM39B TRAF3IP1 TYK2	3 interacting genes: IL13RA1 NAGS PDZK1IP1
Entrez ID		3597	55116
HPRD ID		02125	07662
Ensembl ID		ENSG00000131724	ENSG00000121775
Uniprot IDs		P78552	B3KRL9 Q9BT39 Q9GZU3 Q9NW51
PDB IDs		3BPN 3BPO 4HWB 5E4E
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Activation Positive Regulation Of Mast Cell Degranulation Regulation Of Mast Cell Degranulation P2Y1 Nucleotide Receptor Binding Positive Regulation Of Lymphocyte Activation Regulation Of Cytokine Production Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Immunoglobulin Production Regulation Of Macrophage Activation Positive Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Lung Goblet Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Interleukin-13 Receptor Binding Negative Regulation Of Lung Ciliated Cell Differentiation Cytokine-mediated Signaling Pathway Regulation Of Immunoglobulin Production Positive Regulation Of Exocytosis Response To Other Organism Positive Regulation Of Cold-induced Thermogenesis Interleukin-4 Receptor Activity Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Regulation Of Vesicle-mediated Transport Response To External Biotic Stimulus Regulation Of Alpha-beta T Cell Activation Regulation Of Regulated Secretory Pathway Interleukin-13-mediated Signaling Pathway Interleukin-12 Receptor Complex Negative Regulation Of T-helper 1 Cell Differentiation Regulation Of Cold-induced Thermogenesis Regulation Of Cell Activation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Interleukin-23 Receptor Complex AMPA Glutamate Receptor Clustering Neuroligin Family Protein Binding Negative Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of Leukocyte Proliferation Transforming Growth Factor Beta1 Production Regulation Of Multicellular Organismal Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Exocytosis Interleukin-23-mediated Signaling Pathway Positive Regulation Of NK T Cell Proliferation Morphogenesis Of A Polarized Epithelium D1 Dopamine Receptor Binding Regulation Of Production Of Molecular Mediator Of Immune Response	Interleukin-13 Receptor Complex L-glutamate N-acetyltransferase Activity L-arginine Biosynthetic Process Nitrogen Cycle Metabolic Process Urea Metabolic Process Urea Cycle Arginine Metabolic Process Glutamate Metabolic Process Cytokine Binding Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Cytokine Receptor Activity Positive Regulation Of Immunoglobulin Production Glutamine Family Amino Acid Metabolic Process Amino Acid Biosynthetic Process
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