IL13RA1

Name	interleukin 13 receptor subunit alpha 1
Structure
Interactors	7 interactors: DLG4 IL13 IL4R TMEM132D TMEM39B TRAF3IP1 TYK2
GO Annotations	Cellular Component	Plasma Membrane Interleukin-13 Receptor Complex External Side Of Plasma Membrane Membrane Receptor Complex
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway
Pathways	Interleukin-4 and Interleukin-13 signaling
GWAS	Body mass index ( 28892062 ) Type 2 diabetes ( 30718926 )
Entrez ID	3597
HPRD ID	02125
Ensembl ID	ENSG00000131724
Uniprot IDs	P78552
PDB IDs	3BPN 3BPO 4HWB 5E4E
GO Terms Enriched among Interactors ?	Positive Regulation Of Macrophage Activation Positive Regulation Of Mast Cell Degranulation Regulation Of Mast Cell Degranulation P2Y1 Nucleotide Receptor Binding Positive Regulation Of Lymphocyte Activation Regulation Of Cytokine Production Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Immunoglobulin Production Regulation Of Macrophage Activation Positive Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Lung Goblet Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Interleukin-13 Receptor Binding Negative Regulation Of Lung Ciliated Cell Differentiation Cytokine-mediated Signaling Pathway Regulation Of Immunoglobulin Production Positive Regulation Of Exocytosis Response To Other Organism Positive Regulation Of Cold-induced Thermogenesis Interleukin-4 Receptor Activity Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Regulation Of Vesicle-mediated Transport Response To External Biotic Stimulus Regulation Of Alpha-beta T Cell Activation Regulation Of Regulated Secretory Pathway Interleukin-13-mediated Signaling Pathway Interleukin-12 Receptor Complex Negative Regulation Of T-helper 1 Cell Differentiation Regulation Of Cold-induced Thermogenesis Regulation Of Cell Activation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Interleukin-23 Receptor Complex AMPA Glutamate Receptor Clustering Neuroligin Family Protein Binding Negative Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of Leukocyte Proliferation Transforming Growth Factor Beta1 Production Regulation Of Multicellular Organismal Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Exocytosis Interleukin-23-mediated Signaling Pathway Positive Regulation Of NK T Cell Proliferation Morphogenesis Of A Polarized Epithelium D1 Dopamine Receptor Binding Regulation Of Production Of Molecular Mediator Of Immune Response