KIAA1279 and ATXN2

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIAA1279	ATXN2
Gene Name		KIAA1279	ataxin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytoskeleton	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Polysome Cytoplasmic Stress Granule Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Kinesin Binding	RNA Binding Epidermal Growth Factor Receptor Binding Protein Binding Protein C-terminus Binding Poly(A) RNA Binding
	Biological Process	Mitochondrial Transport Nervous System Development Cell Differentiation	Negative Regulation Of Receptor Internalization Regulation Of Translation RNA Metabolic Process Cerebellar Purkinje Cell Differentiation Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Negative Regulation Of Multicellular Organism Growth Neuron Projection Morphogenesis Homeostasis Of Number Of Cells RNA Transport Neuromuscular Process
Pathways
Drugs
Diseases
GWAS			Beta-2 microglubulin plasma levels ( 23417110) Blood pressure ( 21909110) Celiac disease ( 18311140) Chronic kidney disease ( 20383146) Diastolic blood pressure ( 19430483) Hematocrit ( 19862010) Hypothyroidism ( 22493691) Red blood cell traits ( 23222517) Retinal vascular caliber ( 21060863) Urate levels ( 23263486)
Protein-Protein Interactions		10 interactors: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670	19 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B KIAA1279 LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1
Entrez ID		26128	6311
HPRD ID		13848	03307
Ensembl ID		ENSG00000198954	ENSG00000204842
Uniprot IDs		Q96EK5	Q99700
PDB IDs			3KTR
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chylomicron Remnant Clearance Cellular Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cellular Process G2/M Transition Of Mitotic Cell Cycle Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Microtubule Cytoskeleton Organization Telomere Maintenance Via Telomere Shortening Regulation Of Microtubule-based Process Regulation Of Metabolic Process Response To Heparin Negative Regulation Of Telomere Maintenance Via Telomerase Homocysteine Metabolic Process Replicative Cell Aging Negative Regulation Of Receptor Internalization Regulation Of Nuclear Cell Cycle DNA Replication Cytoplasmic MRNA Processing Body Assembly Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Centriole Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Transcytosis Positive Regulation Of Microtubule Polymerization Cellular Response To Nitric Oxide Regulation Of Cell Cycle Cerebellar Purkinje Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Protein-chromophore Linkage Heterocycle Metabolic Process Regulation Of Telomerase Activity Stress Granule Assembly Response To Nitric Oxide	System Development Multicellular Organismal Development Anatomical Structure Development Focal Adhesion Assembly Developmental Process Adherens Junction Assembly Cell-substrate Junction Assembly Actin Filament Bundle Assembly Regulation Of Metabolic Process Platelet Degranulation Lipid Tube Assembly Adherens Junction Organization
Tagcloud ?		arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr	accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Difference) ?		arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr	accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Intersection) ?