KIAA1279 and DOK2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KIAA1279	DOK2
Gene Name		KIAA1279	docking protein 2, 56kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytoskeleton	Cytosol
	Molecular Function	Protein Binding Kinesin Binding	Receptor Signaling Protein Activity Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Insulin Receptor Binding
	Biological Process	Mitochondrial Transport Nervous System Development Cell Differentiation	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Blood Coagulation Leukocyte Migration
Pathways			Tie2 Signaling Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Entorhinal cortical thickness ( 21116278) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		10 interactors: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670	14 interactors: ABL1 EGFR HCK IL4R INPP5D KIAA1279 LCK LYN NCK1 POT1 RASA1 RET SRC TEK
Entrez ID		26128	9046
HPRD ID		13848	05411
Ensembl ID		ENSG00000198954	ENSG00000147443
Uniprot IDs		Q96EK5	G3V1Q1 O60496
PDB IDs			2D9W 2DLW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chylomicron Remnant Clearance Cellular Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cellular Process G2/M Transition Of Mitotic Cell Cycle Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Microtubule Cytoskeleton Organization Telomere Maintenance Via Telomere Shortening Regulation Of Microtubule-based Process Regulation Of Metabolic Process Response To Heparin Negative Regulation Of Telomere Maintenance Via Telomerase Homocysteine Metabolic Process Replicative Cell Aging Negative Regulation Of Receptor Internalization Regulation Of Nuclear Cell Cycle DNA Replication Cytoplasmic MRNA Processing Body Assembly Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Centriole Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Transcytosis Positive Regulation Of Microtubule Polymerization Cellular Response To Nitric Oxide Regulation Of Cell Cycle Cerebellar Purkinje Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Protein-chromophore Linkage Heterocycle Metabolic Process Regulation Of Telomerase Activity Stress Granule Assembly Response To Nitric Oxide	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Phosphorylation Cell Migration Locomotion Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Protein Autophosphorylation Positive Regulation Of Immune Response Regulation Of Apoptotic Process Peptidyl-tyrosine Autophosphorylation Movement Of Cell Or Subcellular Component Leukocyte Migration Regulation Of Cell Death Immune Response-regulating Signaling Pathway Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Regulation Of Cell Proliferation Immune System Process Cell Surface Receptor Signaling Pathway Response To Lipid Immune Response Intracellular Signal Transduction Single Organismal Cell-cell Adhesion Regulation Of Cytokine Secretion Positive Regulation Of Cell Activation Antigen Receptor-mediated Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Axon Guidance Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of ERK1 And ERK2 Cascade Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Cellular Response To Lipid Blood Coagulation
Tagcloud ?		arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr	adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16 zcchc10
Tagcloud (Difference) ?		arfgef2 arx circonvolutions cobblestone col18a1 delection dieker emx2 filamin flna frontoparietal genetical glioneural gyri heterotopia laminations neuroradiological perisylvian polymicrogyria pseudobulbar rab3gap1 reln schizencephaly srpx2 subaracnoid sulci tbr2 tuba1a vldlr	adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16 zcchc10
Tagcloud (Intersection) ?