KIFBP and DPEP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		KIFBP	DPEP1
Description		kinesin family binding protein	dipeptidase 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton	Extracellular Space Nucleoplasm Plasma Membrane Membrane Apical Plasma Membrane Cell Junction Microvillus Membrane Cell Projection Apical Part Of Cell Extracellular Exosome Side Of Membrane
	Molecular Function	Protein Binding Kinesin Binding Protein Sequestering Activity	Protein Binding Peptidase Activity Metalloexopeptidase Activity Metallopeptidase Activity Zinc Ion Binding Beta-lactamase Activity Hydrolase Activity Dipeptidase Activity GPI Anchor Binding Metal Ion Binding Metallodipeptidase Activity Modified Amino Acid Binding
	Biological Process	Microtubule Cytoskeleton Organization In Utero Embryonic Development Nervous System Development Transport Along Microtubule Central Nervous System Projection Neuron Axonogenesis Cell Differentiation Mitochondrion Transport Along Microtubule Neuron Projection Maintenance	Proteolysis Lipid Metabolic Process Leukotriene Metabolic Process Glutathione Metabolic Process Glutathione Catabolic Process Inflammatory Response Antibiotic Metabolic Process Negative Regulation Of Cell Migration Neutrophil Chemotaxis Homocysteine Metabolic Process Cellular Response To Calcium Ion Cellular Response To Nitric Oxide Lactam Catabolic Process Leukotriene D4 Catabolic Process
Pathways			Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production
Drugs			Cilastatin
Diseases		Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS) Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS			Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Diastolic blood pressure ( 27618447 27618448 27841878) Estimated glomerular filtration rate ( 31451708 30604766 29124443) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Homocysteine levels ( 23824729) Hypertension ( 27618447) Hyperuricemia ( 29124443) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Red vs. brown/black hair color ( 30531825) Serum metabolite levels ( 33031748) Serum uric acid levels ( 29124443) Systolic blood pressure ( 27618447 27841878) Urinary albumin-to-creatinine ratio ( 31511532) Urinary metabolite levels in chronic kidney disease ( 31959995) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670	2 interacting genes: APPBP2 KIFBP
Entrez ID		26128	1800
HPRD ID		13848	01563
Ensembl ID		ENSG00000198954	ENSG00000015413
Uniprot IDs		Q96EK5	A0A140VJI3 P16444
PDB IDs		6ZPG 6ZPH 7RSI 7RSQ 7RYP 7RYQ	1ITQ 1ITU
Enriched GO Terms of Interacting Partners?		Lactam Catabolic Process Antibiotic Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Leukotriene D4 Catabolic Process GPI Anchor Binding Beta-lactamase Activity Glutathione Catabolic Process Modified Amino Acid Binding Metallodipeptidase Activity Photoreceptor Activity Regulation Of Establishment Of Protein Localization To Chromosome Nuclear Telomere Cap Complex Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Telomere Localization Shelterin Complex Meiotic Telomere Clustering Telomeric D-loop Disassembly Ankyrin Repeat Binding Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) 7S RNA Binding TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process U4 SnRNA 3'-end Processing CUT Catabolic Process Poly(A)-dependent SnoRNA 3'-end Processing	Microtubule Associated Complex Intracellular Transport Cul2-RING Ubiquitin Ligase Complex Central Nervous System Projection Neuron Axonogenesis Establishment Of Mitochondrion Localization Central Nervous System Neuron Axonogenesis Neuron Projection Organization Neuron Projection Maintenance Mitochondrion Transport Along Microtubule Kinesin Binding Protein Sequestering Activity Cellular Localization Cytoskeleton Microtubule Motor Activity Establishment Of Localization In Cell Mitochondrion Localization
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