WIPI2 and STRN4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		WIPI2	STRN4
Gene Name		WD repeat domain, phosphoinositide interacting 2	striatin, calmodulin binding protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Nucleoplasm Cytoplasm Autophagic Vacuole Cytosol Extrinsic Component Of Membrane Pre-autophagosomal Structure Membrane Protein Complex	Protein Phosphatase Type 2A Complex Cytoplasm Membrane Dendritic Spine
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Autophagic Vacuole Assembly Autophagic Vacuole Fusion Mitochondrion Degradation Protein Lipidation Cellular Response To Nitrogen Starvation Protein Localization To Pre-autophagosomal Structure Nucleophagy	Biological_process
Pathways
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		6 interactors: ARL6IP1 COPS6 POT1 RABAC1 STRN4 TERF2IP	22 interactors: AK5 ASNS CALM1 CAV1 CLDN12 DDX39B DFFA ECSIT GDF9 JUN KLHDC2 LPPR3 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PPBP SLC25A6 WIPI2 WNT7A
Entrez ID		26100	29888
HPRD ID		15679	18125
Ensembl ID		ENSG00000157954	ENSG00000090372
Uniprot IDs		Q9Y4P8	F5GYK2 F8VYA6 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Capping Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Telomere Formation Via Telomerase Regulation Of Chromosome Organization Protection From Non-homologous End Joining At Telomere Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region DNA Replication Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Cullin Deneddylation Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Protein Deneddylation Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomerase Activity Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Recombination Negative Regulation Of DNA Biosynthetic Process Regulation Of Double-strand Break Repair Protein Localization To Chromosome Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Repair Regulation Of Organelle Organization Positive Regulation Of DNA Replication Regulation Of DNA Recombination	Regulation Of Protein Autophosphorylation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To External Stimulus Response To Organic Cyclic Compound Cellular Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Calcium Ion Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Regulation Of Protein Phosphorylation Response To Wounding Positive Regulation Of Protein Phosphorylation Nitric Oxide Metabolic Process Mitochondrion Organization Reactive Nitrogen Species Metabolic Process Response To Nutrient Levels Regulation Of Nitric-oxide Synthase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Immune System Process Response To Extracellular Stimulus Response To Lipid Response To Transforming Growth Factor Beta Response To Organic Substance Positive Regulation Of Ion Transport Cell Communication Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Cycle Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Prostaglandin Secretion Involved In Immune Response DADP Biosynthetic Process Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Apoptotic DNA Fragmentation Cellular Response To Potassium Ion Starvation L-asparagine Biosynthetic Process
Tagcloud ?		arterivirus autophagosome autophagosomes bronchitis cargos compromising coronavirus diameters generates ibv incorporate lysosome lysosomes map1lc3b mhv nonstructural nsp nsp5 nsp6 nsp7 omegasome organelles prrsv puncta replicase sars sqstm1 starvation torin1
Tagcloud (Difference) ?		arterivirus autophagosome autophagosomes bronchitis cargos compromising coronavirus diameters generates ibv incorporate lysosome lysosomes map1lc3b mhv nonstructural nsp nsp5 nsp6 nsp7 omegasome organelles prrsv puncta replicase sars sqstm1 starvation torin1
Tagcloud (Intersection) ?