ZZZ3 and ZNF212

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZZZ3	ZNF212
Description		zinc finger ZZ-type containing 3	zinc finger protein 212
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Mitotic Spindle ATAC Complex	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Histone Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Dendrite Development Positive Regulation Of Transcription By RNA Polymerase II Neuromuscular Process Controlling Balance Neuron Apoptotic Process General Adaptation Syndrome, Behavioral Process Walking Behavior Response To Alcohol
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	Generic Transcription Pathway
Drugs
Diseases
GWAS		A body shape index ( 34021172) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Height ( 31562340) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Obesity ( 23563607) Platelet count ( 32888494) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 34021172)	Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: BLZF1 CARD9 DNAJB11 EFHC2 EPS8 FAM124A GATA1 GOLGA2 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 PICK1 PPP1R13B TRAF2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513	31 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DRC4 DUSP6 FAM90A1 FHL2 FXR1 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3
Entrez ID		26009	7988
HPRD ID		15907	03859
Ensembl ID		ENSG00000036549	ENSG00000170260
Uniprot IDs		Q8IYH5	A0A090N8N3 B3KQE6 Q9UDV6
PDB IDs		2FC7 2YUM 6E83 6E86
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Identical Protein Binding	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Intracellular Signal Transduction Cellular Response To Amino Acid Starvation Regulation Of Metabolic Process Response To Amino Acid Starvation Negative Regulation Of ERK1 And ERK2 Cascade Nucleoplasm DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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