ZZZ3 and DNAJB11

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZZZ3	DNAJB11
Gene Name		zinc finger, ZZ-type containing 3	DnaJ (Hsp40) homolog, subfamily B, member 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus Nuclear Membrane	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Folding Activation Of Signaling Protein Activity Involved In Unfolded Protein Response MRNA Modification Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Obesity ( 23563607)
Protein-Protein Interactions		16 interactors: BLZF1 DNAJB11 EPS8 FAM124A GATA1 HOXA1 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513	23 interactors: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		26009	51726
HPRD ID		15907	07485
Ensembl ID		ENSG00000036549	ENSG00000090520
Uniprot IDs		Q8IYH5	Q9UBS4
PDB IDs		2FC7 2YUM
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Optokinetic Behavior Abducens Nerve Formation Facial Nucleus Development Basophil Differentiation Eosinophil Fate Commitment Eosinophil Differentiation Rhombomere 4 Development Actin Polymerization-dependent Cell Motility Semicircular Canal Formation Transcriptional Activation By Promoter-enhancer Looping Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Definitive Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Exit From Mitosis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Neurocranium Morphogenesis Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Behavioral Response To Ethanol Outer Ear Morphogenesis	Peptidyl-lysine Modification Catabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signal Transduction Response To Ionizing Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Cellular Response To Amino Acid Stimulus Cellular Heat Acclimation Regulation Of Early Endosome To Recycling Endosome Transport Cytidine To Uridine Editing Cellular Response To Leucine Formation Of Cytoplasmic Translation Initiation Complex Ossification Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Methylation-dependent Chromatin Silencing DNA Modification Positive Regulation Of Reactive Oxygen Species Metabolic Process Histone Lysine Methylation Protein Stabilization Regulation Of Protein Complex Assembly Chromatin Organization Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Regulation Of Methylation-dependent Chromatin Silencing Locomotion Regulation Of Protein Catabolic Process Axon Guidance Signal Transduction By P53 Class Mediator Response To Amino Acid
Tagcloud ?		5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hnf4g hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular hsp40 indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Difference) ?		5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hnf4g hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular hsp40 indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Intersection) ?