ZNF212 and NKX2-3

Number of citations of the paper that reports this interaction (PMID 18255255)
1

Data Source:
BioGRID (two hybrid)

		ZNF212	NKX2-3
Gene Name		zinc finger protein 212	NK2 homeobox 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cellular_component Nucleus
	Molecular Function	DNA Binding Transcription Cofactor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Molecular_function Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter	Leukocyte Homeostasis Plasma Cell Differentiation Transcription, DNA-templated Triglyceride Metabolic Process Biological_process Gland Morphogenesis Macrophage Differentiation Regulation Of Cell Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Crohn's disease ( 18587394 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Inflammatory bowel disease ( 23128233) Red blood cell traits ( 23222517) Ulcerative colitis ( 20228798 20228799)
Protein-Protein Interactions		23 interactors: ATF3 ATF4 CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 GNL1 HBP1 LOC155060 NFKBIA NKX2-3 PPARGC1B PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZZZ3	3 interactors: GTF2A1L SRF ZNF212
Entrez ID		7988	159296
HPRD ID		03859	05992
Ensembl ID		ENSG00000170260	ENSG00000119919
Uniprot IDs		B3KQE6 Q9UDV6	Q8TAU0
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Regulation Of Cellular Process Cellular Response To Stress Cellular Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Organic Substance Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Response To Unfolded Protein Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Endoplasmic Reticulum Stress Regulation Of Bone Resorption Signal Transduction Regulation Of Bone Remodeling Intracellular Receptor Signaling Pathway Trabecula Morphogenesis Signaling Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Chylomicron Remnant Clearance Post-embryonic Digestive Tract Morphogenesis Cellular Response To Stimulus Negative Regulation Of ERK1 And ERK2 Cascade Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway	Contractile Actin Filament Bundle Assembly Negative Regulation Of Beta-amyloid Clearance Cognition Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription By Glucose Regulation Of Beta-amyloid Clearance Cardiac Vascular Smooth Muscle Cell Differentiation Regulation Of Transcription By Glucose Tangential Migration From The Subventricular Zone To The Olfactory Bulb Transcription, DNA-templated Carbon Catabolite Regulation Of Transcription RNA Biosynthetic Process Dorsal Aorta Morphogenesis Dorsal Aorta Development Positive Thymic T Cell Selection Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Primitive Streak Formation MRNA Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Cardiac Muscle Cell Myoblast Differentiation Stress Fiber Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter MRNA Transcription Positive Regulation Of Transcription Via Serum Response Element Binding Coronary Vasculature Development Cardioblast Differentiation Megakaryocyte Development Heart Trabecula Formation Long Term Synaptic Depression Eyelid Development In Camera-type Eye Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Smooth Muscle Cell Differentiation Angiogenesis Involved In Wound Healing Vascular Smooth Muscle Cell Differentiation Regulation Of Water Loss Via Skin Epithelial Structure Maintenance RNA Metabolic Process Cell Migration Involved In Sprouting Angiogenesis Platelet Formation Platelet Morphogenesis Regulation Of DNA-templated Transcription, Initiation Thymic T Cell Selection Megakaryocyte Differentiation Cardiac Myofibril Assembly Gene Expression Aorta Morphogenesis Trophectodermal Cell Differentiation Muscle Cell Cellular Homeostasis Positive Regulation Of Smooth Muscle Contraction
Tagcloud ?		adenocarcinomas assisted ba barrett bas biologically consistently desorption dr5 electrophoresis erbb3 esophageal examples finger flight ihc interesting ionization klf6 lgi1 maldi mucosae spots tandem tof validated validation znf146 znf363
Tagcloud (Difference) ?		adenocarcinomas assisted ba barrett bas biologically consistently desorption dr5 electrophoresis erbb3 esophageal examples finger flight ihc interesting ionization klf6 lgi1 maldi mucosae spots tandem tof validated validation znf146 znf363
Tagcloud (Intersection) ?