RBM45 and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM45	TNPO2
Description		RNA binding motif protein 45	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Nervous System Development Cell Differentiation	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Negative Regulation Of Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		16 interacting genes: ALX1 FANCL FXR1 FXR2 MEMO1 MIR15B MIR200A MIR205 MIR25 MIR29A MIR34B NTAQ1 OGT TNPO2 TRAF1 TXN2	54 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CEBPA CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RBM45 REDIC1 RIPK4 RNF10 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		129831	30000
HPRD ID		09927	04301
Ensembl ID		ENSG00000155636	ENSG00000105576
Uniprot IDs		Q8IUH3	O14787 Q05D48
PDB IDs		7CSX 7CSZ 8WQ3 8WQ5
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Negative Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Translation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Translation Negative Regulation Of Developmental Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Developmental Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endothelial Cell Migration Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement MRNA Destabilization RNA Destabilization Translation Regulator Activity Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Tissue Remodeling Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Amyloid-beta Formation Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Cell Motility Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Regulation Of Endothelial Cell Proliferation Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway	Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Protein Homodimerization Activity
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