CFAP53 and TNIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CFAP53	TNIP1
Gene Name		cilia and flagella associated protein 53	TNFAIP3 interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cilium	Intracellular Nucleus Cytoplasm
	Molecular Function	Molecular_function	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Biological_process	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)
Protein-Protein Interactions		9 interactors: APP CBY1 CCDC85B CEP70 HMG20A PNMA1 TEX11 TNIP1 TRIM23	61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1
Entrez ID		220136	10318
HPRD ID		09958	09216
Ensembl ID		ENSG00000172361	ENSG00000145901
Uniprot IDs		Q96M91	A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025
PDB IDs
Enriched GO Terms of Interacting Partners?		Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Meiotic Gene Conversion Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Negative Regulation Of Neuron Differentiation Axon Choice Point Recognition	Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus
Tagcloud ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Difference) ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Intersection) ?