CFAP53 and TBC1D21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CFAP53	TBC1D21
Description		cilia and flagella associated protein 53	TBC1 domain family member 21
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Manchette Extracellular Region Cytoplasm Centriole Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Centriolar Satellite Ciliary Transition Zone Sperm Flagellum Cell Projection Polymeric Cytoskeletal Fiber Axonemal A Tubule Inner Sheath	Acrosomal Vesicle Cytoplasm Cytoskeleton Cytoplasmic Vesicle Extracellular Exosome Sperm Midpiece
	Molecular Function	Protein Binding	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Cilium Movement Spermatogenesis Determination Of Left/right Symmetry Cell Projection Organization Cell Differentiation Flagellated Sperm Motility Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Flagellum Assembly Manchette Assembly	Spermatogenesis Sperm Axoneme Assembly Cell Differentiation Flagellated Sperm Motility Plasma Membrane To Endosome Transport Sperm Mitochondrial Sheath Assembly Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		29 interacting genes: APP CBY1 CCDC57 CCDC85B CCHCR1 CCNC CEP70 CWF19L2 DRC4 GRIPAP1 HIP1 HMG20A KRT31 KRT34 LDOC1 LENG8 MYOG PARVG PIBF1 PNMA1 RABEP1 SH2D4A TBC1D21 TEX11 TNIP1 TRIM23 TRIM54 TXLNA TXLNB	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		220136	161514
HPRD ID		09958	15473
Ensembl ID		ENSG00000172361	ENSG00000167139
Uniprot IDs		Q96M91	Q8IYX1
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Keratin Filament Cytoskeleton Structural Molecule Activity Regulation Of Cell Projection Organization Astrocyte Projection Morphogenesis Of An Epithelium Negative Regulation Of Cell Projection Organization Regulation Of Neurotransmitter Uptake Epithelial Cell Differentiation Tissue Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Axonemal A Tubule Inner Sheath
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