CFAP53 and CWF19L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CFAP53	CWF19L2
Description		cilia and flagella associated protein 53	CWF19 like cell cycle control factor 2
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GO Annotations	Cellular Component	Spindle Pole Manchette Extracellular Region Cytoplasm Centriole Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Centriolar Satellite Ciliary Transition Zone Sperm Flagellum Cell Projection Polymeric Cytoskeletal Fiber Axonemal A Tubule Inner Sheath	Nucleoplasm Post-mRNA Release Spliceosomal Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cilium Movement Spermatogenesis Determination Of Left/right Symmetry Cell Projection Organization Cell Differentiation Flagellated Sperm Motility Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Flagellum Assembly Manchette Assembly	MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Parkinson's disease progression (cognitive) ( 33111402) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		29 interacting genes: APP CBY1 CCDC57 CCDC85B CCHCR1 CCNC CEP70 CWF19L2 DRC4 GRIPAP1 HIP1 HMG20A KRT31 KRT34 LDOC1 LENG8 MYOG PARVG PIBF1 PNMA1 RABEP1 SH2D4A TBC1D21 TEX11 TNIP1 TRIM23 TRIM54 TXLNA TXLNB	80 interacting genes: ABLIM3 APP AXIN2 BACH2 BRCA1 CALCOCO1 CALCOCO2 CARD10 CARD9 CCDC102B CCDC136 CCDC57 CCDC88B CEP63 CEP70 CEP76 CFAP53 CNTROB CWF19L1 DES DISC1 DRC4 EXOC8 FAM9B FCHO1 FSD2 FXR1 FXR2 GFAP GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOOK1 HOOK2 HSF2BP IKBKG IKZF1 KANK2 KASH5 KIF24 KIFC3 KRT40 LHX3 LHX9 LIMS1 LMNA LZTS1 LZTS2 M1AP MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 PDE4DIP PIBF1 PICK1 PSTPIP1 RINT1 SF3B4 SNW1 STX11 TAX1BP1 TBC1D1 TFIP11 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM37 TRIM54 TRIM9 VIM VPS52 ZBTB8A ZMYND12 ZNF35 ZNF655 ZRANB1
Entrez ID		220136	143884
HPRD ID		09958	13102
Ensembl ID		ENSG00000172361	ENSG00000152404
Uniprot IDs		Q96M91	Q2TBE0
PDB IDs		7UNG 8J07	6ID0 6ID1 8RO2
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Cytoplasm Cytoskeleton Microtubule-based Process Identical Protein Binding Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Centrosome Protein Binding Microtubule Binding Microtubule Organizing Center Microtubule Supramolecular Fiber Organization Microtubule Organizing Center Organization Perinuclear Region Of Cytoplasm Organelle Assembly Cellular Component Assembly Centriole Intracellular Transport Cytosol Cellular Localization Establishment Of Localization In Cell Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Protein Domain Specific Binding Regulation Of Cellular Component Organization Regulation Of Organelle Organization Positive Regulation Of Gene Expression Plasma Membrane Bounded Cell Projection Organization Centriole Replication Regulation Of Centriole Replication Nuclear Pore Localization CBM Complex FHF Complex Regulation Of Long-term Neuronal Synaptic Plasticity Glial Cell Development Negative Regulation Of Cell Cycle Cytoplasmic Microtubule Organization Cilium Assembly Dynein Light Intermediate Chain Binding Negative Regulation Of Cell Cycle Process Membraneless Organelle Assembly Radial Glia-guided Pyramidal Neuron Migration Regulation Of Autophagy Microtubule Nucleation Centriole Assembly Regulation Of Synaptic Plasticity Intermediate Filament Organization
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