PROSER2 and YTHDC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PROSER2	YTHDC1
Description		proline and serine rich 2	YTH N6-methyladenosine RNA binding protein C1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process		Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Recognition MRNA Processing MRNA Export From Nucleus Spermatogenesis RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Primary Follicle Stage MRNA Alternative Polyadenylation
Pathways			Nuclear RNA decay
Drugs
Diseases
GWAS		Fractures (paediatric) ( 32742401) Mean platelet volume ( 27863252)	Mean corpuscular hemoglobin ( 32888494) Obesity-related traits ( 23251661)
Interacting Genes		6 interacting genes: ACTB APP CLIC3 EPS8 POT1 YTHDC1	41 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		254427	91746
HPRD ID		10697	11689
Ensembl ID		ENSG00000148426	ENSG00000083896
Uniprot IDs		D3DRR9 Q86WR7	J3QR07 Q96MU7
PDB IDs			2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YM2 6YM8 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9 7L4X 7L4Y 7P87 7P88 7P8A 7P8B 7P8F 7PJ7 7PJ8 7PJ9 7PJA 7PJB 7PJP 7PJQ 7PO6 8K2E 8Q2Q 8Q2R 8Q2S 8Q2T 8Q2U 8Q2V 8Q2W 8Q2X 8Q2Y 8Q31 8Q32 8Q33 8Q35 8Q37 8Q38 8Q39 8Q3A 8Q3G 8Q4M 8Q4N 8Q4P 8Q4Q 8Q4R 8Q4T 8Q4U 8Q4V 8Q4W
Enriched GO Terms of Interacting Partners?		Brush Border Cellular Component Assembly Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Amyloid-beta Complex Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress Regulation Of Transepithelial Transport Chromatin Remodeling Axonogenesis Regulation Of Norepinephrine Uptake Transporter Regulator Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Growth Cone Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Protein-disulfide Reductase (glutathione) Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Primary Follicle Stage Mammalian Oogenesis Stage MRNA Alternative Polyadenylation Vesicle Protein Localization To Adherens Junction	Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process MRNA Processing MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing Positive Regulation Of RNA Splicing RNA Processing Nucleic Acid Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Domain Specific Binding Non-membrane Spanning Protein Tyrosine Kinase Activity MRNA Binding RNA Binding Spliceosomal Complex RNA Metabolic Process Protein Tyrosine Kinase Activity Macromolecule Metabolic Process SH2 Domain Binding Nucleoplasm Nuclear Speck Nucleic Acid Metabolic Process Regulation Of Macromolecule Biosynthetic Process Protein Phosphorylation Positive Regulation Of Gene Expression Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Protein Kinase Activity Positive Regulation Of MRNA Metabolic Process Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Gene Expression Phosphorylation Regulation Of RNA Metabolic Process Identical Protein Binding Ephrin Receptor Binding Nucleus Regulation Of Primary Metabolic Process Nucleolus Fc-gamma Receptor Signaling Pathway Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Actin Nucleation Activated T Cell Proliferation Ephrin Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?