PROSER2 and YTHDC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PROSER2	YTHDC1
Gene Name		proline and serine rich 2	YTH domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nuclear Body
	Molecular Function		RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process		MRNA Splice Site Selection
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: ACTB APP EPS8 POT1 YTHDC1	34 interactors: ABL1 ADAMTS4 CFH CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPT10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		254427	91746
HPRD ID		10697	11689
Ensembl ID		ENSG00000148426	ENSG00000083896
Uniprot IDs		Q86WR7	J3QR07 Q96MU7
PDB IDs			2YUD
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Positive Regulation Of DNA Strand Elongation Adult Locomotory Behavior Synaptic Growth At Neuromuscular Junction Adult Behavior Collateral Sprouting In Absence Of Injury Actin Polymerization-dependent Cell Motility Telomere Formation Via Telomerase Platelet Activation Locomotory Behavior Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Exit From Mitosis Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Locomotion Homeostatic Process Neuron Remodeling Behavioral Response To Ethanol Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Movement Of Cell Or Subcellular Component Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Axon Guidance Blood Coagulation MRNA Processing Hemostasis Regulation Of Telomerase Activity Single-organism Behavior Rac Protein Signal Transduction Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration RNA-dependent DNA Replication Axonogenesis Copper Ion Homeostasis Suckling Behavior MRNA Metabolic Process Negative Regulation Of DNA Biosynthetic Process	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Protein Autophosphorylation Regulation Of Cell-cell Adhesion RNA Metabolic Process Peptidyl-tyrosine Phosphorylation Regulation Of Wnt Signaling Pathway Gene Expression Viral Process Innate Immune Response Regulation Of Cell Proliferation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Adhesion Anatomical Structure Development Leukocyte Migration Regulation Of Canonical Wnt Signaling Pathway Immune Response Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Cytoplasmic Transport Defense Response Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Activated T Cell Proliferation Phagocytosis Positive Regulation Of Viral Genome Replication Regulation Of Neuron Death Heterocycle Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Nuclear Export Regulation Of T Cell Activation Nucleus Organization Regulation Of Gene Expression Developmental Process Regulation Of Nitrogen Compound Metabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Cellular Process Golgi To Plasma Membrane Transport
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