PSCA and TRARG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PSCA	TRARG1
Description		prostate stem cell antigen	trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Extracellular Exosome Side Of Membrane	Cytoplasm Plasma Membrane Endomembrane System Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Acetylcholine Receptor Regulator Activity Acetylcholine Receptor Binding
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Acetylcholine Receptor Signaling Pathway Regulation Of Neurotransmitter Receptor Activity	Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Establishment Of Localization In Cell Protein Localization To Plasma Membrane Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bladder cancer ( 20972438 24163127 19648920 32117775) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 26098866 30189721) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Schizophrenia ( 33169155) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CATSPERH CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	102 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CARINH CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FAM209A FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SLC10A1 SLC10A6 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC71A2 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4
Entrez ID		8000	286753
HPRD ID		03919	18248
Ensembl ID		ENSG00000167653	ENSG00000184811
Uniprot IDs		O43653	Q8IXB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Sterol Metabolic Process Cholesterol Binding High-density Lipoprotein Particle Binding Establishment Of Protein Localization To Plasma Membrane CDP-diacylglycerol Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Oxysterol Binding Lipid Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Glycerolipid Metabolic Process Cellular Localization Protein Localization To Membrane Trans-Golgi Network Insulin Metabolic Process	Membrane Plasma Membrane Transmembrane Transport Amino Acid Transmembrane Transport Protein Binding Amino Acid Transmembrane Transporter Activity Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport L-amino Acid Transport G Protein-coupled Receptor Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Organic Anion Transport L-alpha-amino Acid Transmembrane Transport Symporter Activity Amino Acid Import Across Plasma Membrane L-glutamine Transmembrane Transporter Activity Glutamine Transport Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Apical Plasma Membrane Monoatomic Ion Transport Basolateral Plasma Membrane Interleukin-8 Binding Sodium Ion Transport Transport Across Blood-brain Barrier Neutral L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity L-glutamine Import Across Plasma Membrane Bile Acid:sodium Symporter Activity Transmembrane Transporter Activity Gamma-secretase Complex G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Inorganic Ion Transmembrane Transport C-X-C Chemokine Receptor Activity Notch Receptor Processing
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