PSCA and CATSPERH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PSCA	CATSPERH
Description		prostate stem cell antigen	catsper channel auxiliary subunit eta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Extracellular Exosome Side Of Membrane	Plasma Membrane Cilium Membrane Motile Cilium CatSper Complex Cell Projection
	Molecular Function	Acetylcholine Receptor Regulator Activity Acetylcholine Receptor Binding	Protein Binding
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Acetylcholine Receptor Signaling Pathway Regulation Of Neurotransmitter Receptor Activity
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bladder cancer ( 20972438 24163127 19648920 32117775) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 26098866 30189721) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Schizophrenia ( 33169155) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CATSPERH CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	13 interacting genes: AQP6 CD3G CD79A EDA2R EMP1 FFAR2 GPR42 KLRC1 MANBAL PSCA SHISAL1 SLC10A6 UPK1B
Entrez ID		8000	100130348
HPRD ID		03919
Ensembl ID		ENSG00000167653	ENSG00000187066
Uniprot IDs		O43653	E9PQX1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Sterol Metabolic Process Cholesterol Binding High-density Lipoprotein Particle Binding Establishment Of Protein Localization To Plasma Membrane CDP-diacylglycerol Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Oxysterol Binding Lipid Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Glycerolipid Metabolic Process Cellular Localization Protein Localization To Membrane Trans-Golgi Network Insulin Metabolic Process	Membrane Immune Response-activating Cell Surface Receptor Signaling Pathway Transmembrane Signaling Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Gamma-delta T Cell Activation Immune Response-activating Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Nitrate Transmembrane Transporter Activity Inhibitory MHC Class Ib Receptor Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Adaptive Immune Response Positive Regulation Of Immune Response Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Innate Immune Response Activating Cell Surface Receptor Signaling Pathway HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Gamma-delta T Cell Receptor Complex IgM B Cell Receptor Complex Natural Killer Cell Inhibitory Signaling Pathway CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Apical Plasma Membrane Urothelial Plaque External Side Of Plasma Membrane Plasma Membrane B Cell Receptor Complex Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Ectodermal Cell Differentiation Bile Acid:sodium Symporter Activity
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