DNAJA4

Description		DnaJ heat shock protein family (Hsp40) member A4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding Hsp70 Protein Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Protein-folding Chaperone Binding
	Biological Process	Protein Folding Response To Heat Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Protein Refolding Negative Regulation Of Inclusion Body Assembly
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 27863252 32888494 28957414) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Serum metabolite levels ( 33031748)
Novel Interacting Genes		2 novel interacting genes: HYKK SKIC8
Interacting Genes		3 interacting genes: BANP ERG SH3BP4
Entrez ID		55466
HPRD ID		09920
Ensembl ID		ENSG00000140403
Uniprot IDs		Q8WW22
PDB IDs
Enriched GO Terms of Interacting Partners?		Amino Acid Kinase Activity Hydroxylysine Kinase Activity Amino Acid Import Ski Complex Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay Cdc73/Paf1 Complex Lysine Catabolic Process
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