ZKSCAN5 and ZSCAN1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZKSCAN5	ZSCAN1
Description		zinc finger with KRAB and SCAN domains 5	zinc finger and SCAN domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Dehydroepiandrosterone sulphate levels ( 21533175) Facial emotion recognition (sad faces) ( 28608620) Femoral neck bone mineral density ( 29499414) Hand grip strength ( 29691431) Hormone measurements ( 23696881) Lumbar spine bone mineral density ( 29499414) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Tacrolimus trough concentration in kidney transplant patients ( 29160300) Total body bone mineral density ( 29304378) Urinary metabolite levels in chronic kidney disease ( 31959995) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: CRK RBM11 RHOB SUV39H1 TNNT1 ZBTB9 ZSCAN1	40 interacting genes: ANKRD55 APP ASH2L ATXN1 CDC5L CDK6 CNOT6L ERCC3 FXR2 GOPC GTF2E1 GTF2H1 HOPX INSM2 MED21 MED31 MED7 NFYC NPAS2 PLRG1 POLR2B POLR2D POLR2E PPARG PPL RFC1 SH2D2A SNW1 SSX3 SSX5 TAF7 TBX20 TIMELESS TRIM31 TTF2 ZKSCAN5 ZNF263 ZNF396 ZNF407 ZSCAN22
Entrez ID		23660	284312
HPRD ID		10318	15897
Ensembl ID		ENSG00000196652	ENSG00000152467
Uniprot IDs		B3KNK8 Q8N718 Q9Y2L8	Q8NBB4
PDB IDs		2EM5 2EMM 2EMZ 2EN3 2EOM 2EON 2EOO 2YSO 2YTG
Enriched GO Terms of Interacting Partners?		Response To Hydrogen Peroxide Response To Oxidative Stress Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Slow-twitch Skeletal Muscle Fiber Contraction	Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus DNA Binding Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process RNA Metabolic Process Positive Regulation Of Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process DNA-templated Transcription Nucleic Acid Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II, Core Complex Negative Regulation Of Transcription By RNA Polymerase II DNA Damage Response Negative Regulation Of RNA Metabolic Process Transcription Preinitiation Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Initiation By RNA Polymerase II Core Mediator Complex Regulation Of DNA-templated Transcription Initiation U2-type Catalytic Step 2 Spliceosome DNA-directed RNA Polymerase Activity Nucleoplasm Transcription Factor TFIID Complex Macromolecule Biosynthetic Process
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