NUP62 and NFX1

Number of citations of the paper that reports this interaction (PMID 11073998)
56

Data Source:
BioGRID (pull down)

		NUP62	NFX1
Gene Name		nucleoporin 62kDa	nuclear transcription factor, X-box binding 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex	Nucleus Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response Viral Process Negative Regulation Of MHC Class II Biosynthetic Process
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6	8 interactors: ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 PABPC1 UBE2N
Entrez ID		23636	4799
HPRD ID		05782	11936
Ensembl ID		ENSG00000213024	ENSG00000086102
Uniprot IDs		P37198	A0JLR2 Q12986
PDB IDs		2H4D
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus	Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Cytokine-mediated Signaling Pathway Viral Life Cycle Pathogenesis Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Response To Cytokine Nuclear Pore Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear Pore Organization Cellular Nitrogen Compound Metabolic Process Pore Complex Assembly RNA Metabolic Process Endomembrane System Organization Nuclear Import Nitrogen Compound Metabolic Process Gene Expression Viral Process Mitotic Cell Cycle Process Cytoplasmic Transport Mitotic Cell Cycle Membrane Organization Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Carbohydrate Metabolic Process Cell Cycle Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Response To Organic Substance Cell Cycle Protein Import Into Nucleus, Docking Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Protein Import Into Nucleus Protein Transport Establishment Of Protein Localization
Tagcloud ?		barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca	acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase
Tagcloud (Difference) ?		barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca	acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase
Tagcloud (Intersection) ?