NFX1 and NUP153

Number of citations of the paper that reports this interaction (PMID 11073998)
56

Data Source:
BioGRID (pull down)

		NFX1	NUP153
Gene Name		nuclear transcription factor, X-box binding 1	nucleoporin 153kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Ligase Activity Poly(A) RNA Binding	DNA Binding Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding Zinc Ion Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein Anchor
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response Viral Process Negative Regulation Of MHC Class II Biosynthetic Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Viral Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport Viral Penetration Into Host Nucleus
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS			Height ( 18391951) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 PABPC1 UBE2N	24 interactors: APC BRCA1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 NFX1 NUP62 NUTF2 NXF1 NXF2 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-1 XPO1 XPO5 XPO7 XPOT
Entrez ID		4799	9972
HPRD ID		11936	04899
Ensembl ID		ENSG00000086102	ENSG00000124789
Uniprot IDs		A0JLR2 Q12986	B4DIK2 F6QR24 P49790 Q4LE47 Q7Z743
PDB IDs			2EBQ 2EBR 2EBV 2GQE
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Cytokine-mediated Signaling Pathway Viral Life Cycle Pathogenesis Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Response To Cytokine Nuclear Pore Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear Pore Organization Cellular Nitrogen Compound Metabolic Process Pore Complex Assembly RNA Metabolic Process Endomembrane System Organization Nuclear Import Nitrogen Compound Metabolic Process Gene Expression Viral Process Mitotic Cell Cycle Process Cytoplasmic Transport Mitotic Cell Cycle Membrane Organization Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Carbohydrate Metabolic Process Cell Cycle Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Response To Organic Substance Cell Cycle Protein Import Into Nucleus, Docking Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Protein Import Into Nucleus Protein Transport Establishment Of Protein Localization	Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Viral Process Nuclear Export Protein Transport Establishment Of Protein Localization Intracellular Transport RNA Transport Establishment Of Localization In Cell RNA Localization Protein Localization To Nucleus Intracellular Protein Transport Protein Localization Protein Import Into Nucleus Nuclear Import MRNA Transport Cellular Localization Protein Import Protein Export From Nucleus Transport Cellular Protein Localization Protein Localization To Organelle Establishment Of Protein Localization To Organelle Cellular Response To Organic Substance Protein Targeting Regulation Of Intracellular Transport Cell Cycle NLS-bearing Protein Import Into Nucleus Regulation Of Cytoskeleton Organization Gene Expression RNA Export From Nucleus Response To DsRNA Response To Organic Substance Cellular Response To Cytokine Stimulus MAPK Import Into Nucleus Viral Life Cycle Response To Growth Factor Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription, DNA-templated Intracellular Transport Of Virus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ribosomal Small Subunit Export From Nucleus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Localization Response To Epidermal Growth Factor Response To Cytokine Regulation Of Intracellular Protein Transport
Tagcloud ?		acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?