NFX1 and NUP214

Number of citations of the paper that reports this interaction (PMID 11073998)
56

Data Source:
BioGRID (pull down)

		NFX1	NUP214
Gene Name		nuclear transcription factor, X-box binding 1	nucleoporin 214kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Ligase Activity Poly(A) RNA Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response Viral Process Negative Regulation Of MHC Class II Biosynthetic Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 PABPC1 UBE2N	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		4799	8021
HPRD ID		11936	00258
Ensembl ID		ENSG00000086102	ENSG00000126883
Uniprot IDs		A0JLR2 Q12986	P35658
PDB IDs			2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Cytokine-mediated Signaling Pathway Viral Life Cycle Pathogenesis Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Response To Cytokine Nuclear Pore Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear Pore Organization Cellular Nitrogen Compound Metabolic Process Pore Complex Assembly RNA Metabolic Process Endomembrane System Organization Nuclear Import Nitrogen Compound Metabolic Process Gene Expression Viral Process Mitotic Cell Cycle Process Cytoplasmic Transport Mitotic Cell Cycle Membrane Organization Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Carbohydrate Metabolic Process Cell Cycle Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Response To Organic Substance Cell Cycle Protein Import Into Nucleus, Docking Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Protein Import Into Nucleus Protein Transport Establishment Of Protein Localization	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?		acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		acetylation catalytic conversely corepressor deacetylase degrading dimethylation dissociates e6 e6ap h3k4 h4 hairpin hdac histones hpv16 htert interacts keratinocytes knockdown ligase mimics msin3a papillomavirus promoter repressor shrna suppresses telomerase	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?